OBJECTIVE To compare the effectiveness of microencapsulated iron(II) fumarate sprinkles (with and without vitamin A), iron(II) sulfate drops, and placebo sprinkles in preventing recurrence of anaemia and to determine the long-term haematological outcomes in children at high risk of recurrence of anaemia 12 months after the end of supplementation. METHODS A prospective, randomized, placebo-con...

BACKGROUND & AIMS Iron deficiency anemia is a common complication of gastric surgery that in certain patients can be refractory to treatment with oral iron and needs to be treated parenterally. METHODS A 48-year woman underwent gastric surgery for a gastric ulcer. She was referred to the nutrition unit for the study and treatment of a 3-year iron deficiency anemia refractory to oral iron supp...

BACKGROUND It is unknown whether iron supplementation in human immunodeficiency virus (HIV)-infected children living in regions with high infection pressure is safe or beneficial. A 2-arm, double-blind, randomized, controlled trial was conducted to examine the effects of iron supplementation on hemoglobin, HIV disease progression, and morbidity. METHODS HIV-infected Malawian children aged 6-5...

OBJECTIVE The aim of this study was to determine the effect of combined calcium and iron versus single iron supplementation on iron status in Bolivian schoolchildren. METHODS Children ages 6 to 10 y old (N = 195), were randomly assigned to receive either 700 mg Ca (as calcium carbonate) plus 30 mg Fe (as ferrous sulfate) (Ca + Fe group) or 30 mg Fe (as ferrous sulfate) (Fe group). The doses w...

Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a CAG repeat expansion that encodes a polyglutamine tract in huntingtin (htt) protein. Dysregulation of brain iron homeostasis, oxidative stress and neurodegeneration are consistent features of the HD phenotype. Therefore, environmental factors that exacerbate oxidative stress and iron dysregulation may potentiate H...

BACKGROUND The aim of this prospective study was to test a new protocol for iron supplementation in haemodialysis patients, as well as to assess the utility of different iron metabolism markers in common use and their 'target' values for the correction of iron deficiency. METHODS Thirty-three of 56 chronic haemodialysis patients were selected for long-term (6 months) i.v. iron therapy at 20 m...

BACKGROUND Iron deficiency anemia is a global health problem, and approximately 50% of anemia is caused by iron deficiency. According to studies, iron supplementation in young females improves iron status by increasing concentration of hemoglobin. To compare of prescribing two methods of iron supplementation administered either on a weekly basis or during menstruation, on hemoglobin level and m...

Background & Aims: The present study deals with an investigation on the effect of iron deficiency anemia and iron supplementation on anemia markers and plasma lipid profiles in pregnant women. Methods: A total of 350 pregnant women were taken and divided into four groups on the basis of haemoglobin levels viz. control (100), mild (100), moderate (100) and severe (50) patients. All the groups we...

OBJECTIVE To examine the effects of iron deficiency and its treatment by iron supplementation or a high iron diet on fatigue and general health measures in women of childbearing age. DESIGN Randomised controlled trial to compare supplement and dietary treatment of iron deficiency. SUBJECTS 44 iron deficient (serum ferritin < 15 microg/L or serum ferritin 15-20 microg/L, plus two of the foll...

Background: Iron-folic acid deficiency is the most common complication during pregnancy. Iron responsible for various health complications among pregnant women. Compliance with IFA supplementation variable across India several factors are associated compliance supplementation. Objective: The objective of this systematic review to assess affecting toward oral iron-folic women in India. Methods: ...