Iron is recognized as an important micronutrient that limits microbial plankton productivity over vast regions of the oceans. We investigated the gene expression responses of Candidatus Pelagibacter ubique cultures to iron limitation in natural seawater media supplemented with a siderophore to chelate iron. Microarray data indicated transcription of the periplasmic iron binding protein sfuC inc...

The 440 fertile eggs, in a completely randomized design were divided into 11 treatments with four replicates and 10 eggs per each replicate. Treatments including: (T1; control; without injection), (T2; injected with 0.3 ml saline 9.0%; sham control), (T3, T4 and T5) 25, 75, 125 ppm Fe-Nano, (T6, T7 and T8) 50, 100, 150 ppm Fe-Nano-Alimet chelate, (T9, T10 and T11) 50, 100, 150 ppm Fe-Aliment ch...

Iron-overload is a major clinical problem in various diseases. Under this condition, serum iron which surpasses the binding capacity of transferrin is present as non-transferrin bound iron and cellular unbound Labile Iron Pool (LIP) is increased. LIP participates in the generation of free radicals, including reactive oxygen species (ROS). Increased ROS, with concomitant decrease in anti-oxidant...

Sorbitol has the effect of promoting nutrient absorption, so it potential to produce excellent fertilizers. In this study, sorbitol calcium chelate was synthesized using as chelating agent. The effects on peanut were investigated, with goal yield and improving utilization fertilizer. Field experiments carried out in Jimo, Shandong Province, China. Four concentrations (0.4, 0.8, 1.6 2.4 g L-1) t...

Iron is an essential cellular nutrient, being a critical cofactor of several proteins involved in cell growth and replication. Compared with normal cells, neoplastic cells have been shown to require a greater amount of iron, thus laying the basis for the promising anticancer activity of iron chelators. In this work, we evaluated the effects of molecules with iron chelation activity on neuroblas...

BACKGROUND Friedreich ataxia is a neurological disease originating from an iron-sulfur cluster enzyme deficiency due to impaired iron handling in the mitochondrion, aconitase being particularly affected. As a mean to counteract disease progression, it has been suggested to chelate free mitochondrial iron. Recent years have witnessed a renewed interest in this strategy because of availability of...

PURPOSE Cell death can be induced by exogenous reactive oxygen species (ROS). Endogenous ROS can also play a role in cell death triggered by agents that are not themselves ROS. One of the most potent ROS-generating systems is the iron-catalyzed Fenton reaction. Herein, the authors tested whether iron plays an important role in cell death induced by diverse stimuli in retinal pigment epithelial ...