OBJECTIVES The objective of this study was to describe the levels of chemerin, irisin and apolipoprotein M (apoM) in women with postmenopausal osteoporosis. METHODS The study included 88 women with postmenopausal osteoporosis. Based on World Health Organization criteria, women with a T-score of ≤ -2.5 were defined as osteoporotic. In this case-control study, postmenopausal women with T-score ...

Retinol-binding protein 4(RBP4), and irisin originally described as an adipocyte-specific hormone, has been suggested to be important link between obesity, insulin resistance diabetes. To test the hypothesis that RBP4, concentrations will higher in obese subject than normal weight. A total of 176 individuals were evaluated, which divided into three groups according BMI. Group I (Normal Weight g...

The Impact of Different Modes Exercise Training on Irisin: A Systematic Review and Meta-Analysis Research

The long-term benefits of exercise for the muscular system are relatively well understood. Inmice,activemuscles turnonaprogramofgeneexpressiondrivenbythe transcription factor PGC1-a, which boosts production of mitochondria and encourages the formation of new blood vessels, increasing the muscle’s ability to respond to increasedworkload.However, exercise alsopromotes ahost of other changesacross...

Background: Irisin is a recently identified myokine that acts like adipokines. It has been revealed to be connected with insulin resistance (IR), obesity, and metabolic syndrome. Objective: To investigate serum, follicular fluid (FF), irisin, IR in lean, overweight, obese women undergoing the intracytoplasmic sperm injection (ICSI) cycle correlate them oocyte embryo quality. Methods: Ninety inf...

Objective(s): Exercise ameliorates the quality of life and reduces the risk of neurological derangements such as Alzheimer’s (AD) and Parkinson’s disease (PD). Irisin is a product of the physical activity and is a circulating hormone that regulates the energy metabolism in the body. In the nervous system, Irisin influences neurogenesis and neural differentiation in mic...

Background: Irisin is a myokine that regulates energy metabolism by inducing browning of adipose tissue. The aim of this study was to evaluate the relationship between irisin level and biochemical parameters of chronic kidney disease (CKD) patients in stage 2 and stage 4. Methods: The research was a cross-sectional study; the study population included patients with CKD who were over 18 years o...

Background: Diabetes and obesity are associated with an increased risk of cardiovascular disease. Irisin is a newly recognized peptidic myokine with anti-obesity and anti-diabetic properties. This study aims to investigate the relationship between serum irisin levels with cardiometabolic biomarkers in patients with type 2 diabetes mellitus (T2DM). Methods: In this comparative cross- sectional s...

Inflammatory bowel diseases (IBDs) are a heterogeneous group of disorders exhibited by two major phenotypic forms: Crohn's disease and ulcerative colitis. Although the aetiology of IBD is unknown, several factors coming from the adipose tissue and skeletal muscles, such as cytokines, adipokines and myokines, were suggested in the pathogenesis of ulcerative colitis; however, it has not been exte...