Recently, indole-3-acetic acid (IAA) has been introduced as a new cancer therapeutic agent through oxidative decarboxylation by horseradish peroxidase (HRP). The purpose of this study was to determine the therapeutic feasibility of IAA/light combination against liver cancer. SK-HEP-1 cells were irradiated with UVB or visible light (518 nm) in the presence of IAA. Cell viability was measured usi...

OBJECTIVE The aim of this work was to verify the usefulness and efficacy of treating superficial vascular lesions of the face using rhodamine intense pulsed light (r-IPL). SUBJECTS AND METHODS Fifty patients suffering from telangiectasias of the face were enrolled and subsequently treated 4 times (every 20 days) with a new intensified r-IPL system optimized at the same wavelength as the dye l...

Portable wireless technology provides many benefits to modern day travelers. Over the years however, numerous reports have cited portable electronic devices (PEDs) as a possible cause of electromagnetic interference (EMI) to aircraft navigation and communication radio systems. PEDs may act as transmitters, both intentional and unintentional, and their signals may be detected by the various radi...

OBJECTIVE To compare loss in sensitivity measured using standard automated perimetry (SAP) with local retinal ganglion cell layer (RGC) thickness measured using frequency-domain optical coherence tomography in the macula of patients with glaucoma. METHODS To compare corresponding locations of RGC thickness with total deviation (TD) of 10-2 SAP for 14 patients with glaucoma and 19 controls, an...

The effect of stimulus rate on the ABR of acoustic tumor (AT) patients was studied. We delivered 90 dB nHL click stimuli to 23 AT patients at stimulus rates of 9.5 Hz, 20 Hz, 40 Hz and 90 Hz, and recorded the ABR at each rate. Normal hearing subjects (42 ears) and sensorineural hearing loss patients (30 ears) were also studied for normative data. The following two parameters were examined: the ...

INTRODUCTION Few studies have evaluated interprofessional learning (IPL) and teamworking in active clinical teams. The aim of this study was to evaluate an IPL programme offered to established clinical teams by assessing team climate before, during and after the intervention. METHODS A previously validated questionnaire, that explored team members' views of team climate, was administered befo...

BACKGROUND More and better interprofessional practice is predicated to be necessary to deliver good care to the patients of the future. However, universities struggle to create authentic learning activities that enable students to experience the dynamic interprofessional interactions common in healthcare and that can accommodate large interprofessional student cohorts. We investigated a large-s...

Postsynaptic receptors in bipolar cells were studied by focal application of glutamate and GABA to the outer and inner plexiform layers (OPL and IPL) under visual guidance in living retinal slices of the tiger salamander. Two different types of conductance change could be elicited in bipolar cells by applying glutamate to the OPL. In off-center cells, which had axon telodendria ramifying in the...

The effect and fate of dry atmospheric deposition on nutrient-starved plankton in the Eastern Mediterranean Sea (EMS; Crete, 2012) was tested by spiking oligotrophic surface seawater mesocosms (3 m3) with Saharan dust (SD; 1.6 g L−1; 23 nmol NOxmg −1; 2.4 nmol PO4mg −1) or mixed aerosols (A; 1.0 g L−1; 54 nmol NOxmg −1; 3.0 nmol PO4mg −1) collected from natural and anthropogenic sources. Using ...

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by neurofibrillary tangles, senile plaques, and loss of synapses. Many studies support the notion that oxidative stress plays an important role in AD pathogenesis. Previous studies from our laboratory employed redox proteomics to identify oxidatively modified proteins in the AD inferior parietal lobule (IPL) and hippocampus....