The molecular dynamics method is used to simulate the formation of ultracold plasma under continuous ionizing irradiation in a quadrupole magnetic field with gradient along axis symmetry equal 0, 30, 150, and 500 G/cm. An increase promotes an density owing trapping some part fast electrons by field.

Background: Interactions of free radicals from ionizing radiation with DNA can induce DNA damage and lead to mutagenesis and carsinogenesis. With respect to radiation damage to human, it is important to protect humans from side effects induced by ionizing radiation.In the present study, the effects of arbutin were investigated by using the micronucleus test for anti-clastogenic activity, to cal...

Ionizing radiation and somatostatin analogues are used for acromegaly treatment to achieve normalization or reduction of growth hormone hypersecretion and tumor shrinkage. In this study, we investigated a combination of somatostatin (SS14) with ionizing radiation of (60)Co and its effect on reparation of radiation-induced damage and cell death of somatomammotroph pituitary cells GH3. Doses of g...

The in vitro effect of O-LM on radiosensitivity of different human cell lines and the in vivo tolerance to high doses of ionizing radiation induced by the combination of Se, Zn and Mn plus Lachesis muta (O-LM) was evaluated. Sprague-Dawley rats received whole-body irradiation with a single dose (2 to 15 Gy) employing a Cs source of 189 TBq (7.7 Gy/min). A half of rats received daily sc O-LM sta...

background: after radiation therapy (rt), some health hazards including dna damages may occur where melatonin can play a protective role due to free radical generation. on the other hand, serious accidental overexposures may occur during rt due to nuclear accidents which necessitate the need for study on exposure to high-dose radiations during treatments. objective: the aim of this study was to...

We examined the modulation of gene expression in Syrian hamster embryo (SHE) cells at various times following exposure to low doses of ionizing radiation. Early passage SHE cells were irradiated in plateau phase (greater than 95% G0-G1 cells) with 21-cGy fission-spectrum neutrons, 75-cGy X-rays, or 90-cGy gamma-rays, none of which induced more than 10% loss in cell viability. RNA harvested at v...

objective: ionizing radiation interacts with biological systems to induce excessive fluxes of free radicals that attack various cellular components. melatonin has been shown to be a direct free radical scavenger and indirect antioxidant via its stimulatory actions on the antioxidant system.the aim of this study was to evaluate the antioxidant role of melatonin against radiation-induced oxidativ...

Ionizing radiation is carcinogenic, but genotype is a key determinant of susceptibility. Mutational DNA damage is generally attributed to cause disease, but irradiation also affects multicellular interactions as a result of poorly understood bystander effects that may influence carcinogenic susceptibility. In this study, we show that the bone marrow of irradiated mice will retain the ability to...

The production of reactive oxygen species (ROS), especially superoxide anions (O2 (·-)), is enhanced in many normal and tumor cell types in response to ionizing radiation. The influence of ionizing radiation on the regulation of ROS production is considered as an important factor in the long-term effects of irradiation (such as genomic instability) that might contribute to the development of se...

Toll-like receptors (TLRs) are pattern recognition receptors that recognize pathogen-associated molecular patterns and are indispensable for antibacterial and antiviral immunity. Our previous report showed that ionizing radiation increases the cell surface expressions of TLR2 and TLR4 and enhances their responses to agonists in human monocytic THP1 cells. The present study investigated how ioni...