Flutamide (Flu) is a chemotherapeutic drug, used for the treatment of prostate cancer. It functions by interfering DNA in fast growing cells and preventing them from reproducing. The present work is focused on the interaction of Flu with single and double stranded DNA at different temperatures and at physiological pH 7.4 (human blood pH). Cyclic voltammetry, square wave voltammetry and UV–visib...

A carbon nanocomposite electrode has been designed by incorporation of montmorillonite nanoclayinto the carbon ionic liquid electrode for the electrochemical determination of amitriptiline . The surface ofthe proposed electrode was characterized by scanning electron microscopy. The presence of ionic liquid asa binder is believed to be responsible for the electrocatalytic activity of the propose...

Identified neurons in different animals express ionic currents at highly variable levels (population variability). If neuronal identity is associated with stereotypical function, as is the case in genetically identical neurons or in unambiguously identified individual neurons, this variability poses a conundrum: How is activity the same if the components that generate it-ionic current levels-ar...

Introduction Conclusions References Tables Figures Back Close Abstract Introduction Conclusions References Tables Figures Back Close Abstract In this work, existing and modified activity coefficient models are examined in order to assess their capabilities to describe the properties of aqueous solution droplets relevant in the atmosphere. Five different water-organic-electrolyte activity coeffi...

Ionic liquid N-ethylpyridinium hydrogen sulfate has been prepared, characterized and used as an efficient recyclable catalyst for the synthesis of a series of indoles and bis(indolyl)methanes. Latter have been further explored for their potential antimicrobial activity against E coli and Bacillus. The ionic liquid used was recycled in the end and its recovery was facilitated b...

Since dialysis of human factor VIII against buffers of low ionic strength yielded two distinct components, and since the factor VIII fraction isolated from normal plasma showed von Willebrand factor activity as defined by the corrective effect on abnormal platelet retention and ristocetin aggregation in von Willebrand's disease, the present studies were performed to determine if the correcting ...

DNA polymerase III from Bacillus subtilis has been purified about 4,500-fold. Disc gel electrophoresis of the purified fraction reveals a single major protein band which co-migrates with the polymerase activity. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of the polymerase yields a single, 166,000 dalton band. The hydrodynamic properties of the enzyme are ionic strength-dependent....

In recent years there has been a great deal of attention paid by researchers in investigating ionic liquids (ILs) mainly due to the tremendous potential that ionic liquids have in reaction and separation technology. Sonic speed is an important thermodynamic property of ionic liquids (ILs) and always chosen as a source to determine other properties. A database for the sonic speed of pure ILs cre...