Background Myocardial scar volume quantification has been shown to predict response to medical, surgical, and device therapy. Phase sensitive inversion recovery (PSIR)-based Late Gadolinium Enhancement (LGE) image reconstruction is clinically attractive for its reduced dependence on accurate prescription of the Time from Inversion (TI time), and is becoming a preferred approach for many centers...

Background A non-contrast 4D Time-Spatial Labeling Inversion Pulse (Time-SLIP) technique [1,2] (3D acquisition and time) has been developed to investigate myocardial bloodflow on healthy volunteers without administration of contrast materials. The technical differences are discussed between our 4D Time-SLIP using tagging aortic root and Flow-sensitive Alternating inversion recovery (FAIR) using...

TARGET AUDIENCE: Researchers and clinicians that study gray matter or use double inversion recovery sequences. PURPOSE: Double inversion recovery (DIR) pulse sequences are commonly used to obtain images of gray matter (GM) by simultaneously suppressing the signal from white matter (WM) and CSF. Unfortunately, these DIR methods are typically slow with low SNR in the GM regions of interest. Recen...

The design of a double inversion recovery (DIR) sequence, to image selectively grey or white brain matter, is described. Suitable choice of inversion times allows either cerebrospinal fluid (CSF) and white matter to be suppressed, to image the cortex alone, or CSF and grey matter to be suppressed, to image the white matter. The DIR sequence was found to give clear delineation of the cerebral co...

A patient undergoing chemotherapy for multiple myeloma had a sudden onset of heart failure. Cardiac magnetic resonance was performed after echocardiography to rule out myocardial late enhancement, which was not detected. In- terestingly, the inversion time of the T1-weighted inversion recovery late enhancement sequence needed to be significantly increased (from the usual 250-300 to 490 ms) to ...

Introduction: Many clinical MRI protocols use the fluid attenuated inversion recovery (FLAIR) contrast to better delineate tissue abnormalities such as white matter lesions. Most FLAIR protocols acquire data in a 2D fashion. FLAIR images are often degraded by patient motion, especially when scanning uncooperative patients. Typical motion patterns induce inter-slice misalignment, ghosting and bl...

This paper presents a new feature selection approach for automatically extracting multiple sclerosis (MS) lesions in three-dimensional (3D) magnetic resonance (MR) images. Presented method is applicable to different types of MS lesions. In this method, T1, T2, and fluid attenuated inversion recovery (FLAIR) images are firstly preprocessed. In the next phase, effective features to extract MS les...

BACKGROUND AND PURPOSE Robust, automated segmentation algorithms are required for quantitative analysis of large imaging datasets. We developed an automated method that identifies and labels brain tumor-associated pathology by using an iterative probabilistic voxel labeling using k-nearest neighbor and Gaussian mixture model classification. Our purpose was to develop a segmentation method which...

Fluid attenuated inversion recovery (FLAIR) with readout-segmented (rs)-EPI Samantha J Holdsworth, Stefan Skare, Kristen Yeom, and Michael E Moseley Lucas Center for Imaging, Department of Radiology, Stanford University, Palo Alto, CA, United States, Clinical Neuroscience, Karolinksa Institute, Stockholm, Sweden, Lucile Packard Children's Hospital, Department of Radiology, Stanford University, ...

We report on MR studies of a 15-year-old girl with moyamoya disease in whom diffuse leptomeningeal enhancement ("ivy sign") was revealed by fluid-attenuated inversion-recovery (FLAIR) and contrast-enhanced imaging. We speculate that the mechanism behind this enhancement is caused by a retrograde slow flow of engorged pial vasculature via leptomeningeal anastomosis. Nevertheless, it remains unkn...