نتایج جستجو برای: invariant nkt cells

تعداد نتایج: 1456579  

2014
Siying Zhu Yuntao Bing Xiaobing Wang Qiao Yu Yipeng Wang Shufang Xu Lu Song Xintao Wang Bing Xia Youqing Zhu Rui Zhou

BACKGROUND Natural killer T (NKT) cells share phenotypic and functional properties with both conventional natural killer cells and T cells. These cells might have an important role in the pathogenesis of ulcerative colitis (UC). The interaction of chemokine ligand 25 (CCL25) with chemokine receptor 9 (CCR9) is involved in gut-specific migration of leukocytes and induces regulatory T cells (Treg...

2015
Robert P. Wilson Megan L. Ives Geetha Rao Anthony Lau Kathryn Payne Masao Kobayashi Peter D. Arkwright Jane Peake Melanie Wong Stephen Adelstein Joanne M. Smart Martyn A. French David A. Fulcher Capucine Picard Jacinta Bustamante Stephanie Boisson-Dupuis Paul Gray Polina Stepensky Klaus Warnatz Alexandra F. Freeman Jamie Rossjohn James McCluskey Steven M. Holland Jean-Laurent Casanova Gulbu Uzel Cindy S. Ma Stuart G. Tangye Elissa K. Deenick

Unconventional T cells such as γδ T cells, natural killer T cells (NKT cells) and mucosal-associated invariant T cells (MAIT cells) are a major component of the immune system; however, the cytokine signaling pathways that control their development and function in humans are unknown. Primary immunodeficiencies caused by single gene mutations provide a unique opportunity to investigate the role o...

Journal: :Proceedings of the National Academy of Sciences 2002

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