We will describe the method of cost-identification analysis, which was performed in a Dutch hospital during a review of antimicrobial drugs usage. In the present Dutch hospital budget system, in-patients' drug costs generate no revenues. Efforts to diminish drug costs result in financial benefit for the institution. To maximize cost containment, efforts are to be directed to all cost components...

Thrombotic microangiopathy is characterized by endothelial changes and microvascular stenosis. Several entities such as pregnancy, infection, connective tissue diseases, and drugs are associated with secondary thrombotic microangiopathy. Recently, new reformulation of Opana ER had been associated with thrombotic microangiopathy when injected intravenously. Here, we report the case of a 37-year-...

The extravasation injuries are uncommon complications during the administration of intravenous therapy in small animal veterinary clinic. However, efflux drugs with vesicant or irritant properties can cause severe and/or irreversible functional and aesthetic changes. correct catheterization technique vigilance fundamental preventing appearance iatrogenic injuries. therapeutic approach to this c...

Microemulsions, comprising oil, water and a surfactant, in association with some co-surfactant, are thermodynamically stable systems. They have found applications large number of chemical pharmacological processes due to their unique properties such as interfacial area, low tension, most importantly, the ability solubilize deliver hydrophobic drugs. In addition oral intravenous route, they suit...

how to cite this article: fallah r, yadegari y, salmani nodushan m. efficacy and safety of intravenous sodium valproate in convulsive status epilepticus in children in shahid sadoughi hospital. iran. j. child. neurol 2012;6(2):39-44.   objective status epilepticus (se) is the most common pediatric neurologic emergency with high mortality and morbidity. there is no consensus on the drug of choic...