OBJECTIVES: To discuss a concept about the current definition and treatment of premature ejaculation. METHODS: A detailed review was performed on the current definition and treatment of premature ejaculation. RESULTS: Several definitions were found, however a consensus on how to define premature ejaculation is lacking. In addition, there are several treatments: daily, on demand and topical agen...

Staphylococcal toxic shock syndrome (STSS) represents a potentially lethal disease, and survival depends primarily on the early initiation of appropriate treatment. As the clinical picture at presentation is usually common, frequently this could lead to misdiagnosis and delays in the initiation of the proper therapy. The case of a 43-years old female who developed a staphylococcal septic shock ...

Objectives: This study aims to compare the newly created intravaginal endometritis model (IVM) with intrauterine (IUM). Methods: E. coli infusion was performed as intravaginally IVM and intrauterinally IUM. The lives of all animals were terminated on 7th day. Histopathological biochemical analyses (GSH, MDA, Endocan, Endoglin) performed. Results: A significant inflammation determined in IUM com...

This study was conducted with two experiments to investigate the efficacy of intravaginal antibiotic or their combination different gonadotropin use on vaginitis and fertility in Berrichon ewes. All ewes (n = 106) were synchronized sponges containing 60 mg medroxyprogesterone acetate for 14 days. For first experiment, 50) received 50 enrofloxacin (TRT) sponge prior insertion no treatment (CON) ...

The bacterial flora of the vagina ten ewes was determined at sponge removal and two days later before insertion fluorogesterone acetate intravaginal sponge. Using E. coli as a marker to species, there significant increase (P<0.05) in population when samples taken were compared, but (P<0.01) decrease season Hertfordshire, England compared later. There no difference (P>0.05) with after r...

Although sexually transmitted pathogens are capable of inducing pathogen-specific immune responses, vaginal administration of nonreplicating antigens elicits only weak, nondisseminating immune responses. The present study was undertaken to examine the potential of CpG-containing oligodeoxynucleotide (CpG ODN) for induction of chemokine responses in the genital tract mucosa and also as a vaginal...

In order to test the hypothesis that macrophages and dendritic cells (DCs) in mucosal tissue play an important role in heterosexual transmission of human immunodeficiency virus, the replication capacities of two simian immunodeficiency viruses (SIVs) were examined in cultured macrophages and DCs as well as in cultured PBMCs in vitro. The virus strains were a T cell-tropic SIV, SIVmac239, and a ...

OBJECTIVE To examine whether a previous caesarean section increases the risk for complications in women undergoing a mid-trimester pregnancy termination by labour induction. DESIGN Retrospective analysis of case records between 1997 and 2002. SETTING Fetal Medicine Unit of a large teaching hospital. POPULATION One hundred and eight women with a previous caesarean section (study group) and...

The addition of antibiotics to intravaginal sponges used to synchronize ewe estrus is currently a recommended practice for the prevention of posttreatment vaginal infections. Application of this antibiotic treatment is usually done without withdrawal periods for milk, but official pharmaceutical instructions do not consider the extra-label use of antibiotics, which could result in the presence ...

Intravaginal inoculation of mice with an attenuated strain of herpes simplex virus type 2 (HSV-2) resulted in vigorous HSV-specific immune responses that protected against subsequent challenge with fully virulent HSV-2 strains. Even in the presence of high titers of HSV-specific Ab, T cell-dependent mechanisms were required for protection of the vaginal mucosae of HSV-immune mice and could be d...