Recent studies have linked fetal exposure to a suboptimal intrauterine environment with adult hypertension. The aims of this study were twofold: 1) to see whether cortisol treatment administered to the ewe for 2 days at 27 days of gestation (term approximately 150 days) resulted in high blood pressure in offspring; 2) to study the effect of the same treatment on gene expression in the brain at ...

AIM To assess the accurate establishment of chorionicity, perinatal complications, and outcome of monochorionic twin pregnancies managed in a tertiary referral center in Croatia and compare the findings with data published for other countries. METHODS The retrospective analysis included data on a total of 24 monochorionic twin pregnancies delivered at the Department between January 1998 and M...

Logan, R. W., Crooks, S. M., Hutchison, J. H., and Kerr, M. M. (1973). Archives of Disease in Childhood, 48, 256. Blood carbonic anhydrase activity in the newborn. Erythrocyte carbonic anhydrase activity was measured in 7 adults, 12 mature newborn infants, 12 preterm low birthweight infants, 9 'dysmature' infants, 33 infants with the respiratory distress syndrome (RDS), and 5 infants who had re...

The authors examined the effects of maternal intrauterine undernutrition on offspring birth weights in a cohort of women born between August 1944 and April 1946 in Amsterdam, The Netherlands. This period included the Dutch Hunger Winter, a war-induced famine. Undernutrition was defined separately for each trimester of pregnancy as an average supply of less than 1,000 calories per day from gover...

Opioids are among the world's oldest known drugs used mostly for pain relief, but recreational use is also widespread. A particularly important problem is opioid exposure in females, as their offspring can also be affected. Adverse intrauterine and postnatal environments can affect offspring development and may lead to various disabilities later in life. It is clear that repetitive painful expe...

male child on the 5th July 1872. She began to complain of slight pains on the morning of the 4th while at breakfast, when the liquor amnii escaped and continued to drain all day. The bowels had been relieved, and the patient felt well. She had all along experienced strong foetal movements. I visited her at 11 a.m. ; the os was about the size of a sixpence. I was sent for again in the evening, a...

INTRODUCTION Disseminated intravascular coagulation due to placental abruption with intrauterine fetal death is not uncommon. It can result in increased maternal mortality rates and the need for hysterectomy or greater transfusion volumes if the delivery is not completed within six to eight hours. However, consensus is lacking regarding the delivery approach for cases in which delivery is prolo...

Objective. There is an asymmetric allocation of technology and other resources for infertility services. Intrauterine insemination (IUI) is a process of placing washed spermatozoa transcervically into the uterine cavity for treatment of infertility. This is a review of literature for the potential use of IUI as a basic infertility treatment in technology-limited settings. Study design. Review o...

Unintended pregnancy persists as a major public health problem in the United States. Although lowering unintended pregnancy rates requires multiple approaches, individual obstetrician-gynecologists may contribute by increasing access to contraceptive implants and intrauterine devices. Obstetrician-gynecologists should encourage consideration of implants and intrauterine devices for all appropri...

This study analyses the influence of female and male patient age and human menopausal gonadotrophin (HMG) requirements on clinical pregnancy rates and live birth rates with ovulation stimulation using HMG in combination with intrauterine insemination (IUI). In this study, 363 consecutive HMG/IUI treatment cycles in 184 patients carried out at a university fertility centre were analysed in a ret...