BACKGROUND The impact of the intrauterine environment on the developmental programming of adult female reproductive success is still poorly understood and potentially underestimated. Litter size variation in a nonhuman primate, the common marmoset monkey (Callithrix jacchus), allows us to model the effects of varying intrauterine environments (e.g. nutrient restriction, exposure to male womb-ma...

The developmental origins of the metabolic syndrome have been established through the consistent observation that small-for-gestational age and large-for-gestational age fetuses have an increased risk for hypertension and related metabolic disorders later in life. These phenotypes have been reproduced in various species subjected to a range of intrauterine insults and ongoing research is direct...

background : there are various variables such as the duration and the client consistency' in using a special contraceptive method as well as some individual determinants. which play important roles in optimal using of different contraceptive methods. iud cu- 380a is a safe and an effective method used by 12.5% urban women in east azarbaijan. correlation between continuation rate of using iud cu...

intrauterine device (iud), a conventional method of contraception is rarely associated with uterine perforation and extra uterine dislocation. a 29 years old woman complaining of vaginal bleeding was referred for pelvic mass identified in ultrasound. the mass was confirmed with ct scan. in laparatomy we found an iud in cul-de-sac and pelvic mass was apparently an organized hematoma. transmigrat...

introduction: prevalence of infertility in general population is around 15-10 percent. intra- uterine insemination (iui) is one method for treatment of infertility. success rate of this method is affected by different factors. past studies have shown that induction of ovulation and iui has increased significantly the chance of pregnancy in the infertile couple, especially male factor infertilit...

Human epidemiological and experimental animal studies show that suboptimal environments in fetal and neonatal life exerts a profound influence on physiological function and risk of disease in adult life. The molecular, cellular, metabolic, endocrine and physiological adaptations to intrauterine nutritional conditions result in permanent alterations of cellular proliferation and differentiation ...

Intrauterine progestins have many important current and potential gynecologic applications. This article describes the evidence for use of intrauterine progestin for common gynecologic conditions beyond its important role in contraception. The pharmacology of and selection criteria for use of the levonorgestrel intrauterine device is discussed, and the evidence for use of intrauterine progestin...

background: the levonorgestrel-releasing iud can help the treatment of dysmenorrhea by reducing the synthesis of endometrial prostaglandins as a conventional treatment. objective: this study was performed to assess the frequency of dysmenorrhea, satisfaction and quality of life in women using mirena iuds as compared to those using copper iuds. materials and methods: this double-blind randomized...

BACKGROUND To study in a large-scale cohort with prospective data the associations between psychosocial stress during pregnancy and placenta weight at birth. Animal data suggest that the placenta is involved in stress-related fetal programming. METHODOLOGY/PRINCIPAL FINDINGS We defined a priori two types of psychosocial stress during pregnancy, life stress (perceived burdens in major areas of...