Cellular myxoma and grade I myxofibrosarcoma are mesenchymal tumours that are characterized by their abundant myxoid extracellular matrix (ECM). Despite their histological overlap, they differ clinically. Diagnosis is therefore difficult though important. We investigated their (cyto) genetics and ECM. GNAS1-activating mutations have been described in intramuscular myxoma, and lead to downstream...

OBJECTIVE To compare the effectiveness of nasal diamorphine spray with intramuscular morphine for analgesia in children and teenagers with acute pain due to a clinical fracture, and to describe the safety profile of the spray. DESIGN Multicentre randomised controlled trial. SETTING Emergency departments in eight UK hospitals. PARTICIPANTS Patients aged between 3 and 16 years presenting wi...

OBJECTIVE Treatment of severe hypoglycemia with loss of consciousness or seizure outside of the hospital setting is presently limited to intramuscular glucagon requiring reconstitution immediately prior to injection, a process prone to error or omission. A needle-free intranasal glucagon preparation was compared with intramuscular glucagon for treatment of insulin-induced hypoglycemia. RESEAR...

A rare case of intramuscular lipomatosis of the tongue with intramuscular invasion in a 42 year old man is presented. The literature is reviewed and the clinical features, pathology, and treatment are discussed briefly.

BACKGROUND This multicenter, assessor-blinded, randomized study was done to confirm and extend a pilot study showing that intramuscular rocuronium can provide adequate tracheal intubating conditions in infants (2.5 min) and children (3 min) during halothane anesthesia. METHODS Thirty-eight infants (age range, 3-12 months) and 38 children (age range, 1 to 5 yr) classified as American Society o...

intramuscular haemangiomas are benign malformations of blood vessels occurring in skeletal muscles. Because of the rarity of these lesions, their deep location and variable clinical presentation, they often pose diagnostic difficulties. We herein present the first reported case of intramuscular haemangioma occurring in the levator anguli oris muscle. A 26-year-old man was referred to our Depart...

To prevent reinfection with hepatitis B virus after orthotopic liver transplantation, patients receive long-term intravenous anti-HBs immunoprophylaxis. We compared the pharmacokinetics of intravenously and intramuscularly administered commercially available hepatitis B virus immunoglobulins. The study group consisted of 12 patients on immunoprophylaxis after orthotopic liver transplantation, w...

introduction : supplementation with minerals like calcium has been shown to be effective in preventing bone loss and increasing bone density. thus, it can be assumed that if calcium supplementation is paired with bisphosphonates, greater benefit can be achieved. in this context, we decided to perform this animal study on ovariectomized rats to assess whether bisphosphonate supplemented with cal...

I treated cynomolgus monkeys with topical echothiophate iodide twice daily for several months. Accommodative responses to topical or intramuscular pilocarpine were determined after ciliary ganglion or cholinergic nerve blockade. During echothiophate treatment, there was little or no accommodative response to intramuscular pilocarpine doses which were near maximal in nonechothiophate-treated eye...

OBJECTIVE To assess the level of adherence to Adult Intramuscular Injections Protocol by health care providers of Civil Hospital Karachi. METHODS This analytical cross sectional study was conducted in July and August of 2009, at Civil Hospital Karachi after institutional permission. Data was collected with a pre tested data collection tool. Two hundred and seventeen house officers and nurses ...