Tumor Therapy In article number 2106606, Nan Qin, Tiger H. Tao, and co-workers report a heterogenous silk microneedle patch to spatiotemporally sequentially deliver multiple therapeutic drugs for hemostasis, anti-angiogenesis, apoptosis of brain tumor cells. Drug release kinetics are well-defined by tuning the crosslinking degree applying trigger transcranial NIR-light irradiation. This biodegr...

Pregnancy and maternal brain tumors are an infrequent finding and a rare clinical combination. We present a case of a pilocytic astrocytoma (PA) diagnosed during the second trimester of pregnancy. This tumor is rare and is usually diagnosed in children. The occurrence in an adult presents different challenges regarding the long term behaviour of the tumor. Brain tumors during pregnancy are usua...

We evaluated the effects, on immunity and survival, of injection of interferon (IFN)-alpha-transfected dendritic cells (DC-IFN-alpha) into intracranial tumors in mice immunized previously with syngeneic dendritic cells (DCs) pulsed either with ovalbumin-derived CTL or T helper epitopes. These immunizations protected animals from s.c. challenge with ovalbumin-expressing M05 melanoma (class I+ an...

CONTEXT Radiotherapy is frequently administered as adjuvant treatment in patients with clinically nonfunctioning pituitary adenomas (NFPAs). However, concerns have been raised about potential long-term side effects, including cerebrovascular events (CVEs) and secondary intracranial tumors. OBJECTIVE The aim of this study was to analyze the risk of CVEs, secondary intracranial tumors, and mort...

BACKGROUND Meaningful segmentation of intracranial lesions can be of assistance for planning open navigated microneurosurgical procedures, as well as for radiotherapy. Meaningful segmentation, however, may be hampered by lack of computational power. The respective segmentation method should be based on state-of-the-art mathematical tools, and it should be suitable for real applications. METHO...

Interestingly, intracranial tumors in infancy and childhood that you really wait for now is coming. It's significant to wait for the representative and beneficial books to read. Every book that is provided in better way and utterance will be expected by many peoples. Even you are a good reader or not, feeling to read this book will always appear when you find it. But, when you feel hard to find...

Hemangiopericytomas (HPCs) are rare aggressive tumors, thought to comprise 2 to 3% of all primary meningeal tumors and 0.4% of all intracranial tumors.1–5 It was first reported by Stout and Murray6 and occurs mostly in soft tissue, including brain meninges primarily. Histologically, intracranial HPC arises from malignant transformation of Zimmerman’s pericytes, supportive cells that help form t...

background: tumors involving the hand skeleton are rare. however, a basic knowledge of hand tumors is necessary for every clinician. this is due to the importance of distinguishing typical benign tumors from life or limb threatening malignant ones. methods: this study is a review of 99 cases of osseous hand tumors presented to the department of orthopedic surgery, imam khomeini hospital in tehr...

PURPOSE To review the clinical data, imaging findings, and intermediate outcomes of a series of children with hemorrhagic vasculopathy after treatment for intracranial neoplasia. METHODS We retrospectively analyzed the medical records and imaging examinations of 20 pediatric patients (ages 1 to 15 years) with intracranial neoplasia in whom delayed intracranial hemorrhage developed after crani...

Atrial myxomas are benign tumors, and most of them are located in the left atrium. Left atrial myxoma commonly leads to cerebral embolic ischemic stroke. The intracranial aneurysm is rarely associated with myxoma. There are few reports about left atrial myxoma leading simultaneously to both anterior and posterior circulation infarction, and multiple intracranial saccular aneurysms. Now we repor...