PURPOSE This study extends previous community-based studies on the prevalence and clinical characteristics of chemical intolerance in a sample of primary care clinic patients. We evaluated comorbid medical and psychiatric disorders, functional status, and rates of health care use. METHODS A total of 400 patients were recruited from 2 family medicine clinic waiting rooms in San Antonio, Texas....

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Thirteen out of 49 patients suspected of having specific food intolerance after withdrawal and reintroduction of specific foods, were further subjected to double blind placebo controlled food challenges. Only three of these subjects were thus shown to have proven specific food intolerance. Of the remaining 10, nine were strong 'placebo reactors'. The study suggests that a small number of patien...

BACKGROUND Lactose intolerance resulting in gastrointestinal symptoms is a common health concern. Diagnosis and management of this condition remain unclear. PURPOSE To assess the maximum tolerable dose of lactose and interventions for reducing symptoms of lactose intolerance among persons with lactose intolerance and malabsorption. DATA SOURCES Multiple electronic databases, including MEDLI...

Abstract In the era of rising populist sentiment, deep social and political polarisations, a growing crisis online harms, numerous scholars share concern about impact such uncivil forces on health liberal democracy. This article argues that we should first normatively distinguish between incivility intolerance. We contend core problem society is intolerance, not incivility. then empirically ana...

Methods In a large, prospective JIA cohort, potential predictors (clinical variables and single nucleotide polymorphisms) were determined at the time of MTX start. The Methotrexate Intolerance Severity Score was employed to measure MTX intolerance in the first year of treatment. MTX intolerance was most prevalent at 6 or 12 months after MTX start. This was defined as the outcome for the predict...

We have read with great interest the article about food intolerance and respiratory symptoms in young adults by WOODS et al. [1]. We have conducted a survey, which has not yet been published, with the aim of comparing the clinical features of patients with bronchial asthma and those with analgesic intolerance accompanying asthma. We also asked the patients whether they ever had any reactions to...

BACKGROUND Noninvasive ventilation (NIV) intolerance is one reason for NIV failure. However, the characteristics, predictors, and outcomes of NIV intolerance are unclear. METHODS A prospective observational study was performed in the respiratory intensive care unit of a teaching hospital. Subjects with acute respiratory failure who used NIV were enrolled. Initially, continuous use of NIV was ...