background and objectives: previous studies have shown the antinociceptive effect of morphine in animal models, but the specific anti-pain consequence of the abuse drug in female animals is unclear. the present research showed the morphine antinociception in female wistar rats using formalin test. materials and methods: subjects were 40 female wistar rats purchased from pasteur institute of ira...

transcutaneous electrical nerve stimulation (tens) is an analgesia inducing method with increasing applications in clinical procedures. in this study we tried to evaluate the role of the adrenergic system and its different adrenoceptor subtypes in tens-induced analgesia. two types of low and high frequency electrical stimuli were used in rats through needle electrodes, inserted at the base of t...

It has been suggested that placebo analgesia involves both higher order cognitive networks and endogenous opioid systems. The rostral anterior cingulate cortex (rACC) and the brainstem are implicated in opioid analgesia, suggesting a similar role for these structures in placebo analgesia. Using positron emission tomography, we confirmed that both opioid and placebo analgesia are associated with...

Creating a just culture Key words: just culture, TeamSTEPPS, human error, briefing, huddle. Circulating while administering moderate sedation/analgesia Key words: moderate sedation/analgesia, RN circulator. Monitoring RN leaving room during administration of moderate sedation Key words: moderate sedation/analgesia, propofol. Screening for obstructive sleep apnea before administering moderate se...

Background: The regional anaesthesia has lot of benefits compared to general for lower abdominaland limb surgeries. Epidural is an ideal anesthetic technique abdominal and lowerlimb additives are used with Anesthetics Early onset action, To prolong the duration ofaction, Analgesia Improving quality block.Aims Objectives: aim this study was clinical efficacy Dexmedetomidine versus Fentanylas add...

women. The ideal labour analgesia technique should dramatically reduce the pain of labour, while allowing the parturient to actively participate in the birthing experience. In addition, it should have minimal effect on the fetus or the progress of labour. New labour analgesia techniques approach this goal. This lecture will review these new methods of pain relief for the parturient and will hig...

We have previously reported that stress analgesia sensitive to and insensitive to opiate antagonists can be differentially produced in rats by varying the severity or temporal pattern of inescapable footshock. In these studies, we give further evidence for the opioid and non-opioid bases of these paradigms of stress analgesia. We find that naloxone-sensitive analgesia demonstrates tolerance wit...

Editor’s points † Genetic polymorphism in the m-opioid receptor can affect systemic opioid analgesia. † The effects of the A118G polymorphism on analgesia and pruritus after intrathecal fentanyl for labour analgesia were compared in two ethnically distinct populations. † While there was no effect of the genetic polymorphism, there was a marked effect of the ethnically distinct groups on duratio...