There are many activities currently being undertaken in the field of laboratory medicine under the broad heading of "harmonization". These include traceability of results to international reference standards, processes to align results from assays where traceability has not been achieved (analytical harmonization) and international or national clinical guidelines based on studies from many part...

Hospital-based medical records are abstracted to create International Classification of Disease (ICD) coded discharge health data in many countries. The 'main condition' is not defined in a consistent manner internationally. Some countries employ a 'reason for admission' rule as the basis for the main condition, while other countries employ a 'resource use' rule. A few countries have recently t...

More than 50% of all gynecologic cancers can be classified as rare tumors (defined as an incidence of fewer than six per 100,000). Improved understanding of the molecular pathogenesis of tumors increases the proportion of rare tumors and creates challenges in optimizing the design of clinical trials. Novel trial designs are needed to take forward the development of new treatments in rare tumors...

Abstract The IUPAC International Award For Advances In Harmonized Approaches To Crop Protection Chemistry recognizes individuals in government, intergovernmental organizations, academia, and industry who have exercised personal leadership for outstanding regulatory, public policy, and/or educational contributions supporting international harmonization of crop protection chemistry. award is admi...

After a long-standing tradition of analytical quality and analytical quality control programs, most medical laboratories that are aware of the need for total quality management, are experiencing new systems designed to assure quality throughout the entire total testing process, from the pre-analytical to the post-analytical steps. The availability of a new International Standard, ISO 15189:2003...

Equivalence of results issued by clinical laboratories can be achieved standardization or harmonization. The generation comparable allows common reference intervals between using different measurement procedures and materials for calibration trueness control. aim this article is to describe the state art metrological traceability in laboratory medicine, currently highlighted through guidelines ...

The OIE is the international standard-setting organization for animal health and zoonoses. It addresses the control and prevention of important and emerging diseases primarily by collecting and disseminating relevant animal health information worldwide, and by adopting and publishing sanitary standards and recommendations for animals and animal products. The OIE’s Information System is aimed at...

Here in we introduce the European Partnership for Alternative Approaches to Animal Testing (EPAA) and its activities, which are focused on international cooperation toward alternative methods. The EPAA is one of the leading organizations in Europe for the promotion of alternative approaches to animal testing. Its innovative public-private partnership structure enables a consensus-driven dialogu...