objective: β-thalassemia is caused by absence or reduction of β-globin chain synthesis. one of the effective therapeutic methods for this disease can be gene therapy by viral vectors. the capacity of lentiviral vectors is approximately 8 kb, we designed a 6 kb construct containing mini lcr and β-globin gene instead of lcr region. the aim of this study is to make a recombinant lentiviruses conta...

a two-year laboratory study on the biology (including self-fertilization) of bulinus truncatus, the intermediate host of schistosoma haematobium, s. bovis and paramphistomum microbotrium in iran, has revealed information on the longevity, reproduction, hatchability rate, hatching time during various months of the year, and growth and mortality rates of this snail. it was found that the reproduc...

We prove a functional limit theorem for the rescaled occupation time fluctuations of a (d, α, β)branching particle system (particles moving in R according to a symmetric α-stable Lévy process, branching law in the domain of attraction of a (1 + β)-stable law, 0 < β < 1, uniform Poisson initial state) in the case of intermediate dimensions, α/β < d < α(1 + β)/β. The limit is a process of the for...

Despite the importance of benzoic acid (BA) as a precursor for a wide array of primary and secondary metabolites, its biosynthesis in plants has not been fully elucidated. BA formation from phenylalanine requires shortening of the C(3) side chain by two carbon units, which can occur by a non-β-oxidative route and/or a β-oxidative pathway analogous to the catabolism of fatty acids. Enzymes respo...

Multifunctional nanocomposites Ag/Al2O3/TiO2@β-cyclodextrin-graphene oxide (AATG) incorporating graphene sheets, TiO2, and Ag/Al2O3 nanoparticles were prepared in two steps. We benefited from the inherent properties of β-cyclodextrin to create a stable aqueous solution capable self-assembling situ grown TiO2 on nanosheets. catalysts with high surface-to-volume ratio by combustion technique urea...

Abstract Although tin monoxide (SnO) is an interesting compound due to its p -type conductivity, a widespread application of SnO has been limited by narrow band gap 0.7 eV. In this work, we theoretically investigate the structural and electronic properties several phases under high pressures through employing van der Waals (vdW) functionals. Our calculations reveal that metastable (β-SnO), whic...

An (α, β)-community is a subset of vertices C with each vertex in C connected to at least β vertices of C (self-loops counted) and each vertex outside of C connected to at most α vertices of C (α < β) [9]. In this paper, we present a heuristic (α, β)-Community algorithm, which in practice successfully finds (α, β)-communities of a given size. The structure of (α, β)-communities in several large...

The prediction of the correct β-sheet topology for pure β and mixed α/β proteins is a critical intermediate step toward the three dimensional protein structure prediction. The predicted beta sheet topology provides distance constraints between sequentially separated residues, which reduces the three dimensional search space for a protein structure prediction algorithm. Here, we present a novel ...