Abstract Hydroxysafflor yellow A is extracted from Carthamus tinctorius L., Asteraceae, and has extensive pharmacological properties. In this study, interleukin-1 beta was used to establish the osteoarthritis model in vitro , impacts of hydroxysafflor on cell were analyzed. CCK8 measure viability, flow cytometry evaluate apoptosis reactive oxygen species. An enzyme-linked immunosorbent assay pe...

Introduction: Curcumin, a natural antioxidant, has anti-inflammatory and protective effect on a large number of diseases like cancers and hepatic disorders in oxidative stress conditions by collecting free oxygen radicals and increasing intracellular glutathione. The aim of this study was to determine the effects of curcumin on the level of IL-17 and IL-10 cytokines in intrahep...

A fully automated and efficient radiosynthesis of a novel interleukin-2 radioconjugate from single FASTLab™ cassette.

BACKGROUND: Psoriasis is frequently accompanied by metabolic syndrome. Effect of anti-tumor necrosis factor therapies on increases in body weight well-known. Data the effects interleukin-17 inhibitors are limited. Authors determined effect anti-interleukin-17 composition and serum lipid inflammatory parameters among severe psoriatic patients. METHODS: Thirty-five patients were enrolled. Twenty-...

Objectives. This study was performed to find changes in the plasma cytokine profile of neuroresuscitation patients with ventilator-associated pneumonia, and search for prognostic markers effectiveness antibacterial treatment pneumonia. Materials methods. A two-center clinical study, that included 73 aged 19 82 years neurosurgical neurological pathology signs pneumonia (VAP) conducted. On 1st 3r...

Background: Interleukin-1 receptor antagonist (IL-1Ra) also known as Anakinra is a of IL-1 especially IL-1β. IL-1β increased in infected COVID-19 patient groups. This study aimed that the IL-1Ra contained Conditioned Medium Wharton’s Jelly Mesenchymal Stem Cells (CM-WJMSCs) has potential to inhibit which one cytokine storms occur COVID patients through an in-silico approach. Objective: aims det...