نتایج جستجو برای: interferon regulatory factor 7 irf7

تعداد نتایج: 1617638  

2014
Shun Lu Barbara Pardini Bowang Cheng Alessio Naccarati Stefanie Huhn Veronika Vymetalkova Ludmila Vodickova Thomas Buchler Kari Hemminki Pavel Vodicka Asta Försti

Interferon (IFN) signaling has been suggested to play an important role in colorectal carcinogenesis. Our study aimed to examine potentially functional genetic variants in interferon regulatory factor 3 (IRF3), IRF5, IRF7, type I and type II IFN and their receptor genes with respect to colorectal cancer (CRC) risk and clinical outcome. Altogether 74 single nucleotide polymorphisms (SNPs) were c...

Journal: :Expert Reviews in Molecular Medicine 2013

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2002
Fan Xiu Zhu Sonya M King Eric J Smith David E Levy Yan Yuan

Interferons constitute the earliest immune response against viral infection. They elicit antiviral effects as well as multiple biological responses involved in cell growth regulation and immune activation. Because the interferon-induced cellular antiviral response is the primary defense mechanism against viral infection, many viruses have evolved strategies to antagonize the inhibitory effects ...

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