نتایج جستجو برای: interferon alpha

تعداد نتایج: 256607  

Journal: :Infection and immunity 1981
A M Attallah K Zoon T Folks J Huntington T J Yeatman

To identify the active molecule in human alpha interferon preparations, we performed several studies, using both partially purified interferon and homogeneous interferon. Our results indicated that there is little difference between the partially purified and the homogeneous interferon preparations in terms of antiviral activity, inhibition of deoxyribonucleic acid synthesis in human neoplastic...

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Journal: :Journal of Biological Chemistry 1985

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Journal: :Acta Neuropsychiatrica 2002

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Journal: :Bone Marrow Transplantation 2006

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2009
Vaheh Oganesyan Melissa M. Damschroder Kimberly E. Cook Herren Wu William F. Dall’Acqua

Recombinant human interferon alpha-2A (rhIFN-alpha-2A) has been crystallized in complex with the recombinantly produced Fab fragment of a therapeutic monoclonal antibody (MEDI545; IgG1/kappa) which targets several human interferon alpha subtypes. This constitutes the first reported crystals of a human type I interferon bound to an antibody. The orthorhombic crystals belonged to either space gro...

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Journal: :Revista da Associacao Medica Brasileira 2012
Thamy Jay Garcia Paulo Henrique Schmidt Lara Tauy Pereira Morimoto Mauricio Higasiaraguti Andréia Maruzo Perejão Munir Akar Ayub

OBJECTIVE To review and compare side effects of hepatitis C treatment with pegylated interferon and ribavirin at the CRIE of the Hospital Mário Covas (Santo André), São Paulo, Brazil, from February 23 to May 5, 2011. METHODS Cross-sectional study through questionnaire, with a non-probability sample comprised of 340 patients that had received at least one dose of the medication. RESULTS Side...

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Journal: Iranian Journal of Virology 2017
Aida Gholoobi, Amin Hooshyar, Ehsan Aryan, Hadi Farsiani, Kiana Ketabi, Majid Darroudi, Mohammad Sadegh Damavandi, Mohsen Abdoli, Sajad Naseri, Zahra Meshkat,

Background and Aims: Iron oxide nanoparticles are among the most effective tools which can replace current medical techniques for diagnosis and treatment of various diseases. Hepatitis C infection is one of the main health problems in the world, affecting around 3% of the world's population. This infection can develop into liver cirrhosis and liver cancer over the time in 80% of patients. In t...

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Journal: :Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 2000
K Koseki M Nakano M Takaiwa T Kamata J Yosida

We report 3 cases of suicide attempts in postoperative patients with renal cancer after alpha interferon withdrawal. In the first patient, depression occurred during interferon therapy, and remained after interferon withdrawal. A suicide attempt occurred 7 months after interferon withdrawal. In the second and third patients, depression did not occur during interferon therapy, but suicide attemp...

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Journal: :Genitourinary medicine 1993
L J Eron M B Alder J M O'Rourke K Rittweger J DePamphilis D J Pizzuti

OBJECTIVE To determine whether interferon alpha-2a, when utilised as adjuvant chemotherapy following ablation of condylomata acuminata (genital warts) by cryotherapy, is effective in the prevention of recurrences. DESIGN Randomised, placebo-controlled, double-blind study. Statistical analysis was by 2-tailed Fisher's Exact Test. PATIENTS 97 patients with recurrent condylomata acuminata. I...

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Journal: :Journal of Virology 2017

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