نتایج جستجو برای: inhibition proliferation
تعداد نتایج: 481256 فیلتر نتایج به سال:
In this study, the cytotoxic effects of aqueous and ethanolic extracts of Sedum album L. on human stomach cancer cell line (AGS) and breast cancer cell line (MCF-7) were evaluated by MTT, BrdU and TUNEL assays. The results demonstrated that both extracts had antiproliferative and apoptotic effects in a dose-dependent manner. The MTT assay data revealed that the AGS cell underwent more cytotoxic...
Severe lesions in vessels need to be treated with implantable interventional devices such as vascular stents, which should anti-coagulantion, anti-proliferation and promoting endothelialisation. Nitric oxide (NO), a physiological gas signalling molecule, play an important role revascularisation. Catalysing the release of NO from endogenous donors has already been widely favoured treatment strat...
Platelet-derived growth factor (PDGF) plays an essential role in proliferation of vascular smooth muscle cells (VSMCs). The Rb/E2F and TSC/mTOR pathways contribute to the proliferation of VSMCs, but its exact roles in PDGF-induced proliferation are unclear. In this study, we demonstrated the roles of Rb/E2F and TSC/mTOR pathways in PDGF-induced proliferation in VSMCs. We found that PDGF stimula...
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