Background: Apart from its role in bone health, recent developments have shown that vitamin D also has anti-inflammatory properties, and therefore may a inflammatory bowel disease (IBD) children. Objectives: To determine the effect of supplementation on activity pediatric patients with IBD. Design: Random-effects meta-analysis Data Sources: Studies were searched at Cochrane Library, PubMed, EBS...

Patients with inflammatory bowel disease (IBD) are increasingly becoming interested in nonpharmacologic approaches to managing their disease. One of the most frequently asked questions of IBD patients is what they should eat. The role of diet has become very important in the prevention and treatment of IBD. Although there is a general lack of rigorous scientific evidence that demonstrates which...

Introduction Blau Syndrome (Blau) is a granulomatous auto-inflammatory disease caused by mutations in NOD2 that have been proposed to result in phosphorylation of RIP2 kinase and the production of pro-inflammatory cytokines. Such monogenic diseases can bring to light pathways that are also likely to be involved in more genetically complex diseases. For example, increased RIP2 phosphorylation ha...

CLINICAL CASE An 18 year-old-woman presented with abdominal pain, diarrhea, and ptosis in her left eye. Nuclear magnetic resonance imaging (NMRI) and the study of cerebrospinal fluid detected no abnormalities. Colonoscopy revealed a Crohn's disease (CD) confirmed by histological examination of biopsies. Ocular symptoms improved after appropriate treatment of the underlying CD. DISCUSSION Infl...

K ABSTRACT: The aim of this work was to investigate the possible influence of the recently described CT60 A/G dimorphism of the CTLA4 (cytotoxic T-lymphocyte antigen 4) gene in the susceptibility to two different autoimmune inflammatory intestinal disorders, inflammatory bowel disease (IBD) and celiac disease. We analyzed a case-control cohort composed of 528 Spanish patients with IBD (284 with...

Background: Bidirectional relationships between the immune system, nervous system, and psychological processes likely exist in inflammatory bowel disease (IBD) because stress can affect IBD, and IBD is associated with an increased risk of psychological difficulty. The field of psychoneuroimmunology (PNI) sheds light on specific mechanisms that are involved in these relationships, and this resea...

Endoscopy is a valuable clinical tool for the clinician who takes care of patients with inflammatory bowel disease (IBD). The role of endoscopy in the diagnosis, management, and treatment of IBD is discussed in this review. The central role that colonoscopy plays in screening for colon cancer in patients with longstanding IBD is also addressed.

inflammatory bowel disease (ibd) is a chronic disease of unknown etiology, in which genetic factors, seem to play an important role in the disease predisposition and course. assessment of tumor necrosis factor (tnf-α) gene polymorphisms in many populations showed a possible association with ibd. considering the genetic variety in different ethnic groups, the aim of the present study was to inve...

background: considering the unknown etiology of inflammatory bowel disease (ibd), the epidemiologic evaluation may help to identify the causative agents of the disease. genetic (ethnic) and environmental (e.g., geographic) factors in iran may influence the incidence of the disease. the objective of this study was toâ  determine the demographic and clinical characteristics of the ibd in the city...

Journal of Family Planning and Reproductive Health Care 2003: 29(3) What is inflammatory bowel disease (IBD)? Inflammatory bowel disease (IBD) refers to two distinct disorders – Crohn’s disease (CD) and ulcerative colitis (UC).1 These two disorders have distinct clinical and pathological features but their cause is unknown. In patients with large bowel disease only there may be difficulty disti...