Reproductive tract tumours, specifically leiomyoma, are commonly found in female rhinoceroses. Similar to humans, tumour growth in rhinoceroses is thought to be sex hormone dependent. Tumours can form and expand from the onset of ovarian activity at puberty until the cessation of sex-steroid influences at senescence. Extensive tumour growth results in infertility. The aim of this study was to d...

Two strategies to control mosquito-borne diseases, such as malaria and dengue fever, are reducing mosquito population sizes or replacing populations with disease-refractory varieties. We propose a genetic system, Semele, which may be used for both. Semele consists of two components: a toxin expressed in transgenic males that either kills or renders infertile wild-type female recipients and an a...

We determined the effect of a GnRH vaccine on reproductive function of sexually mature 5-month female and male domestic swine. The vaccine, GonaCon, developed at NWRC contains a GnRH peptide conjugated to KLH, combined with AdjuVac adjuvant also developed at NWRC. Four groups of ten females were given single IM immunizations either of 800μg GnRH vaccine, 1600μg GnRH vaccine, a prime and boost o...

Heightened mammalian target of rapamycin complex 1 (mTORC1) activity by genetic deletion of its direct inhibitor, Tsc1, is associated with aberrant development and dysfunction of the female reproductive tract in mice. Here, we compared the phenotypes of mice with conditional deletion of Tsc1 in the female reproductive tract by either progesterone receptor (PR)-Cre (Tsc1(PR(d/d))), which inactiv...

a:4:{s:9:"Objective";s:285:"Some potentially modifiable factors, such as appropriate informing process to infertile patients, can affect their infertility knowledge and information. This study aimed to assess infertility information provided to Iranian infertile people undergoing assisted reproductive treatment.";s:19:"MaterialsAndMethods";s:871:"In this cross-sectional study, participants recr...

Women with prior pregnancy but no live birth are inconsistently termed as either 'primary infertile' or 'secondary infertile' in psychosocial studies of infertile women. The goal of this study was to discover whether infertile women who had experienced pregnancies but no live births were more similar in attitudes and behaviour to infertile women who had not experienced pregnancies or to those w...

BACKGROUND Infertility is defined as the inability to achieve the pregnancy within a year of unprotected intercourse. Infertility is a complex issue and different factors such as stress oxidative can be involved in this problem. So, any attempt to neutralize oxidative stress would be helpful in the treatment of infertility. Melatonin is a known scavenger of free radicals. OBJECTIVE The aim of...

BACKGROUND The present study investigated the effect of emotionally focused therapy (EFT) on factors contributing to emotional distress among infertile couples. MATERIALS AND METHODS In this semi-experimental study, the subjects consisted of 12 Iranian couples: six infertile men and six infertile women. They were assessed as depressed, anxious and stressful individuals using depression, anxie...

Background Infertility can affect the quality of life of infertile couples. The aim of this study was to develop and measure psychometric properties of “Quality of Life in Infertile Couple Questionnaire” (QOLICQ). Methods This study was conducted in two qualitative and quantitative phases. Qualitative method involved semi-structured interviews of a purposive sample of 34 infertile couples. A co...

OBJECTIVE To investigate levels of seminal oxidative stress (OS) and sperm quality in a group of infertile men with a history of cigarette smoking. DESIGN A prospective clinical study. SETTING Male infertility clinic, Urological Institute, the Cleveland Clinic Foundation, Cleveland, Ohio. PATIENT(S) Infertile men who smoked cigarettes (n = 20), infertile men who were nonsmokers (n = 32), ...