OBJECTIVES To study neonatal outcomes following buprenorphine/naloxone and methadone exposure during pregnancy. METHODS This study is a retrospective review of clinical and demographic information of 58 infants whose mothers were treated with buprenorphine/naloxone and 92 infants whose mothers were treated with methadone for opioid dependence during pregnancy. RESULTS Gestational age, birth...

This paper explores the introduction of a screening test to highlight impaired immune system status for newborn infants and its efficacy as a preventative clinical measure. Moreover, it is suggested that screening of the infantile immune system has the potential to highlight susceptibility to a range of infant and childhood diseases, bestowing an opportunity to introduce early intervention to r...

aintaining acid base balance presents a considerable challenge to the growing neonate. The infant ust ingest protein for growth and development. The metabolism of sulfur containing amino acids eads to the production of protons that must be secreted by the kidney. In addition, the formation of ydroxyapatite for the mineralization of growing bone also leads to acid production. Thus, the rowing in...

Feeding a neonate with a complete cleft lip and palate is difficult pursuit due to communication between oral cavity and nasal cavity. A multidisciplinary approach is required to manage the complex problems involved in case of such neonates and their families. Present case is of a 1-day-old neonate having complete bilateral cleft lip and palate for which palatal obturator was constructed. A ste...

Sepsis is a significant cause of morbidity and mortality in neonates and adults, and the mortality rate doubles in patients who develop cardiovascular dysfunction and septic shock. Sepsis is especially devastating in the neonatal population, as it is one of the leading causes of death for hospitalized infants. In the neonate, there are multiple developmental alterations in both the response to ...

introduction: congenital hypothyroidism is the most common cause of mental retardation in the world. the presence of hypothyroidism in fetal is lead to abnormalities in major organs, including nervous system and central skeleton. aim of this study was to investigate epidemiologic situation of neonatal hypothyroidism in ilam province between 2005 -2011. materials and methods: this was a cross-se...

introduction: some studies have suggested correlation between mpv index and inflammatory diseases such as rheumatoid arthritis in adults. though bronchopulmonary dysplasia is also an inflammatory disease which develops in preterm neonates with respiratory distress syndrome, we decided to study the possible correlation between the mean platelet volume (mpv) and the occurrence of bronchopulmonary...

Spontaneous preterm birth includes birth that follows preterm labor, preterm spontaneous rupture of membranes, and cervical insufficiency, but does not include indicated preterm delivery for maternal or fetal conditions (5). The preterm birth rate (birth at less than 37 completed weeks of gestation per 100 total births) increased more than 20% from 1990 to 2006. However, decreases in birth rate...

The aim of this work was to review the published data on the pharmacokinetics of cephalosporins in neonates to provide a critical analysis of the literature as a useful tool for physicians. The bibliographic search was performed for articles published up to December 3, 2010, using PubMed. In addition, the book Neofax: A Manual of Drugs Used in Neonatal Care by Young and Mangum was consulted. Th...

BACKGROUND AND OBJECTIVES: The utility of a lung ultrasound score (LUS) has been described in the early phases neonatal respiratory distress syndrome (RDS). We investigated as tool to monitor status preterm neonates throughout course RDS. METHODS: Preterm neonates, stratified 3 gestational age cohorts (25–27, 28–30, and 31–33 weeks), underwent at weekly intervals from birth. Clinical data, supp...