INTRODUCTION ..................................................................................... 173 I. THE PROBLEM ............................................................................ 174 A. What Happened to the Daily Newspaper? .......................... 175 B. What’s an iPad, and Why Do Newspapers Care? ............... 177 C. Why the iPad Might Not Be a Savior ........................

Limitations of retrospective analyses R.S. Hoffman Poison centers provide poison prevention and safety information, professional education, and assistance with the diagnosis and treatment of poisoning. These invaluable efforts are linked to medically and legally mandated record keeping, which entails continuous and archived collection of data over time. Surrounded by gigabytes of information re...

A platinum(II)-based major groove binder [Pt(II)(C^N)(C≡NR)(2)](+) (HC^N = 2-phenylpyridine (phpy), R = 2-naphthyl) was identified as a potent human topoisomerase IIα poison. It stabilizes the covalent TopoIIα-DNA cleavage complex and induces cancer cell death with potency significantly higher than the widely clinically used TopoIIα poison Vp-16.

background: during the one-year period from may 2008 to may 2009, a nationwide shortage developed which rabies vaccine was not being produced by the manufacturers. in order to manage existing supply, a protocol was established wherein an authorization was required from the regional poison center before vaccine could be administered to a patient. methods: the georgia poison center internal datab...