background in clinical practice, the level of sensory block in spinal anesthesia in opium abusers is lower than that in non-abusers because of adaptive changes caused by opium use. objectives the aim of this study was to investigate the level of sensory block resulting from the intrathecal administration of 0.5% bupivacaine in opium abuser patients undergoing lower extremity and lower abdominal...

to study the role of preoperative intravenous magnesium sulphate in decreasing post-cesarean pain and opioid requirement during first 24hrs.in a double blind randomized clinical trial, prior to induction of general anesthesia, fifty elective cesarean candidates were randomly assigned to one of the two groups of placebo or magnesium sulfate. after surgery visual analogue scale (vas) and infused ...

background emergence agitation (ea) is a common problem in pediatric anesthesia. the current study evaluated the effect of intravenous lidocaine combined with propofol or thiopental sodium to control ea by sevoflurane in children. objectives the current study aimed to compare the effectiveness of two anesthesia regimen propofol–lidocaine and thiopental sodium lidocaine to control sevoflurane-in...

To compare efficacy of spontaneous breathing with pressure support and volum e-c ontrolled mandatory ventilation during combined general anesthesia using desflurane without muscle relaxants. Subjects Methods. 100 patients were included in the study. All underwent lo w-t raumatic operations on lower limbs under supraglottic air devices Immediately prior to induction anesthesia, randomly divided ...

BACKGROUND The administration of opioids before induction of general anesthesia can be considered as a problem in cesarean section. The aim of this study was to compare the effects of intravenous Fentanyl as a premedication before induction of general anesthesia versus placebo on maternal hemodynamic parameters and on the first and fifth minutes Apgar score in the neonates in elective cesarean ...

CONTEXT Rapid opioid detoxification with opioid antagonist induction using general anesthesia has emerged as an expensive, potentially dangerous, unproven approach to treat opioid dependence. OBJECTIVE To determine how anesthesia-assisted detoxification with rapid antagonist induction for heroin dependence compared with 2 alternative detoxification and antagonist induction methods. DESIGN, ...

inhalant anaesthetics are used widely for producing general anaesthesia in animals and humans.. approximately 20% of halothane uptake is metabolised via oxidative and reductive pathways during and following halothane anaesthesia in humans. fifteen clinically healthy dogs were assigned in three groups (group 1, 2and 3) randomly. all dogs were anesthetized with halothane three times that was repe...

BACKGROUND During closed-loop control, a drug infusion is continually adjusted according to a measure of clinical effect (e.g., an electroencephalographic depth of hypnosis (DoH) index). Inconsistency in population-derived pediatric pharmacokinetic/pharmacodynamic models and the large interpatient variability observed in children suggest a role for closed-loop control in optimizing the administ...