this study was conducted to assess the preventive effect of aqueous extract of berberis integerrima bge. root (aebir) on liver damage and oxidative stress induced by diabetes mellitus in rats. forty male rats were divided into 5 groups as follows: 1- normal (n); 2- normal + barberry (n+b) (they received barberry root extract for 6 weeks); 3- diabetic (d) (they received streptozotocin (stz), 65 ...

objective: atorvastatin has the pleiotropic effects, including anti-inflammation and antioxidant. therefore, this study considered to examine the effects of atorvastatin on nf-қb expression, as a main transcription factor for expression of inflammatory cytokines, in hyperglycemia-induced nephropathy in rat. materials and methods: twenty four male wistar rats were randomly divided into four grou...

introduction: due to the relation between structure and function of renal glomeruli, the study of glomeruli is very important to the understanding of initiation and progression of diabetic glomerulopathy. it seems that glomeruli disappear during the course of diabetic nephropathy without leaving recognizable corpuscles. this study was aimed to show diabetes mellitus effects on changes in renal ...

Objective(s): Reproductive dysfunction is a consequence of diabetes. Diabetes is associated with changes in testicular tissue. Sesame oil contains large amounts of polyunsaturated fatty acids and lignin with antioxidant activity, vitamin E, and monounsaturated fatty acid (MUFA). The present study investigated the effects of sesame on testis histology and male reproductive parameters in streptoz...

background bioflavonoids are well known for their multi directional biologic activity including antidiabetic effect. it has been demonstrated that flavonoids can act as insulin secretagogue or insulin mimetic agents. objectives this experimental study was designed in arak university of medical sciences, arak, iran, to investigate the effects of biochanin a (a bioflavonoid) on fasting blood gluc...

Introduction: Hyperalgesia is one of the symptoms of diabetic neuropathy and is considered as a major clinical complaint in these patients which could affect the quality of their life. Since attenuation of hyperalgesia is very important, in the present study the possible analgesic effect of aqueous extract of coriander was investigated in male rats with streptozotocin-induced diabetes using sta...

an in vivo experiment was conducted to study the effects of probiotic bacillus coagulans spores, with and without prebiotic, inulin, on gastrointestinal (gi) microbiota of healthy rats and its potentiality to survive in the gi tract. forty-eight male wistar rats were randomly divided into four groups (n=12) and fed as follows: standard diet (control), standard diet supplied with 5% w/w long cha...

The aim of the study was to compare the serum levels of adiponectin and interleukin-6 (IL-6) in insulin-treated diabetic rats with or without periodontitis. Forty male Wistar rats were randomly divided into 2 groups (20 rats each): a) insulin-treated diabetic group (control, DI) and b) insulin-treated diabetic periodontitis group (test, DIP). Diabetes was induced, and insulin treatment was init...