The objective of this study was to determine the chronology of changes in blood pressure in renalhypertension induced by solid plexiglass clips in rats. Saw blades with the thickness of 0.21-0.22 mm wereused to make clips sized 4 × 2 × 2 mm from a piece of 2-mm thick plexiglass. Rats were subjected to shamoperation or left renal arterial clipping, and 1, 2, 3 and 4 weeks later blood pressure, a...

I n tr o d u c tio n T E cfi'ccls o f the systemic adminis­ tration o f crude papain to young rabbits were first described by Thomas (1956), who noted that the most obvious change was a bilateral collapse o f the ears. This effect was lost within a few days. Subsequently llu lth and Westerborn (1959) and Merkow and Lalieh (1961), who iLsecl crude papain in single and repeated (loses, and in dif...

The bone marrow (BM) is an important site for the interrelated processes of hematopoiesis, granulopoiesis, erythropoiesis, and lymphopoiesis. A wide variety of microbial challenges are associated with profound changes in this compartment that impact on hematopoietic differentiation and mobilization of a variety of cell types. This article reviews some of the key pathways that control BM homeost...