in this study, the effect of α-adrenoceptor agents on imipramine-induced antinociception was investigated using formalin test. intraperitoneal (i.p.) administration of imipramine at different doses (10-80 mg/kg) induced antinociception in both phases of formalin test. in addition, intracerebroventricular (i.c.v.) injection of imipramine (1, 5, and 10 µg/rat) did not elicit any effect, although ...

malvastrum tricuspidatum is recommended in ayurveda and folklore medicine for the management of gastric ulcers. therefore, the purpose of the study was to investigate the antiulcer effect of whole plant extract of malvastrum tricuspidatum (mte) on ethanol (etoh)-induced, aspirin (asp)-induced, cold-restraint-stress (cru) and pylorus--ligation(pl)-induced gastric ulcer models in rats. aqueous ex...

seizure activity has been proposed to result in the generation of reactive oxygen species (ros), which then contribute to seizure-induced neuronal damage and eventually cell death. although the mechanisms of seizure-induced ros generation are unclear, mitochondria and cellular calcium overload have been proposed to have a crucial role. we aim to determine the sources of seizure-induced ros and ...

Quantum addition circuits are considered being of two types: (1) Toffoli-adder which use only classical reversible gates (controlled-not and Toffoli), (2) QFT-adder based on the quantum Fourier transformation. We present a systematic translation QFT circuit into Toffoli-based adder. This result shows that has fundamentally same fault-tolerance cost (e.g., T count) as most cost-efficient Toffoli...

classical trajectory (monte carlo) calculation is used to calculate collision rate constants of ion-quadrupolar molecule interactions for the h¯+c2h2 system. the method presented here takes into account the effect of the induced dipole-induced dipole potential on ion-quadrupolar molecule collision rate constants. it is also assumed that the colliding particles have a definite size. the thermal ...

In the present study the effect of intracerebroventricular (ICV) injection of cerulein, an agonist of CCK receptor and proglumide, a receptor antagonist for hyperalgesia induced by sciatic nerve ligation were investigated in mice. Subcutaneous administration of morphine caused anti-nociception in both intact and nerve-ligated mice. However, the response to opioids was lower in ligated mice as c...

aloe buettneri a. berger is commonly used in traditional togolese medicine to treat inflammatory and gastric ulcers. the present study examined the gastro-protection effect of the hydro-alcoholic extract of a. buettneri on mucus production and gastric ph. a gastric ulcer is induced by ethanol 95° alone (1 ml/kg body weight), after pre-treatment with indomethacin (300 mg/kg) or by utilising l-na...

this study represents an attempt to determine the prevalence of exercise-induced bronchospasm among soccer player children. a total of 234 soccer player boys of all soccer schools from shahr-rey enrolled in this study. they did not have any history of a recent or chronic respiratory tract disease, a history of allergic diseases, and history of bronchodilator drugs consumption during the 24 hour...