INTRODUCTION Incision and drainage of symptomatic emergency patients with facial swelling is painful even after local anesthetics are administered. The purpose of this prospective, randomized, double-blind study was to compare the pain of infiltration and the pain of an incision and drainage procedure of a buffered versus a nonbuffered 4% lidocaine formulation in symptomatic emergency patients ...

BACKGROUND Brain-derived neurotrophic factor (BDNF) from spinal microglia is crucial for aberrant nociceptive signaling in several pathological pain conditions, including postoperative pain. We assess the contribution of spinal microglial activation and associated BDNF overexpression to the early post-incisional nociceptive threshold. METHODS Male Sprague-Dawley rats were implanted with an in...

BACKGROUND Neonatal surgical injury triggers developmentally regulated long-term changes that include enhanced hyperalgesia and spinal microglial reactivity after reinjury. To further evaluate priming of response by neonatal hindpaw incision, the authors investigated the functional role of spinal microglial p38 mitogen-activated protein kinase after reincision in adult rodents. METHODS Planta...

BACKGROUND The authors previously reported changes in electroencephalographic bicoherence during isoflurane anesthesia combined with epidural anesthesia. Here, they examined the influence of noxious stimuli on electroencephalographic bicoherence as well as on the Bispectral Index (BIS) and the 95% spectral edge frequency (SEF95). METHODS The authors enrolled 48 elective abdominal surgery pati...

BACKGROUND Double-eyelid blepharoplasty is a popular aesthetic surgery in Asians. However, the buried suture technique is associated with complications related to implantation of the suture thread. The present study was performed to identify optimal surgical suture removal techniques in Japanese patients with suture-related complications after buried suture double-eyelid blepharoplasty. METHO...

OBJECTIVES Compare circular defect with dog-ear deformities excision (CDDE) technique to 3:1 fusiform excision technique when removing facial lesions to analyze which technique provides superior wound closure. METHODS Identical 1-cm circular skin defects were created on bilateral cheek, forehead, and parietal scalp on three fresh cadavers. Similarly, using four fresh cadavers, identical 2-cm ...

BACKGROUND To learn more about pain mechanisms produced by surgery, responses of wide dynamic range (WDR) and high threshold (HT) dorsal horn neurons were studied before and after an incision. For this study, an incision was made in a mechanically insensitive area of the receptive field (RF) of the dorsal horn neuron in the plantar aspect of the foot and changes in mechanical response propertie...

purpose : to evaluate the safety and efficacy of limbal relaxing incisions (lris) for corneal astigmatism correction during phacoemulsification methods : 24 eyes of 24 patients with the mean age of 65.71 years (range: 55 to 83 years) with senile cataracts and mean corneal astigmatism of 1.9±0.83 diopters (d) (range: 1.5 to 3.5 d) were included in this study. all lris were performed during phaco...

tragacanth gum is one of the most important medicinal and industrial productsof rangelands and is obtained from the incision of gum tragacanth-producing astragalusincluding astragalus keyserlingii. the conservation of astragalus species in rangelandshas a special place in terms of economic profit and soil conservation. the increase in priceof gum tragacanth in recent years and more attention of...