PURPOSE Screening tool of older people's prescriptions (STOPP) and screening tool to alert to right treatment (START) criteria were first published in 2008. Due to an expanding therapeutics evidence base, updating of the criteria was required. METHODS We reviewed the 2008 STOPP/START criteria to add new evidence-based criteria and remove any obsolete criteria. A thorough literature review was...

Multimorbidity and polypharmacy are increasingly prevalent across healthcare systems and settings as global demographic trends shift towards increased proportions of older people in populations. Numerous studies have demonstrated an association between polypharmacy and potentially inappropriate prescribing (PIP), and have reported high prevalence of PIP across settings of care in Europe and Nor...

BACKGROUND Systems for identifying potentially inappropriate medications in older adults are not immediately transferrable to advanced dementia, where the management goal is palliation. The aim of the systematic review was to identify and synthesise published systems and make recommendations for identifying potentially inappropriate prescribing in advanced dementia. METHODS Studies were inclu...

Over the last few years, there has been a rapid and steadily expanding demographic explosion in the elderly population in France. When the most dynamic segment of this growth is considered, i.e. patients aged 80 years or more (who, moreover, usually have several diseases), under- or over-prescribing and/or inappropriate prescribing are identified. Three short- and medium-term recommendations ar...

BACKGROUND The administration of many drugs concurrently to elderly patients is a well-known problem in geriatrics and involves numerous risks. One way to reduce polypharmacy is to provide information to physicians in order to modify their prescribing practices. The main objective of this study was to evaluate the impact of an intervention program that targeted physicians with the aim of reduci...

This review will address the management of hyponatremia caused by the syndrome of inappropriate antidiuretic hormone secretion (SIADH) in hospitalized patients. To do so requires an understanding of the pathogenesis and diagnosis of SIADH, as well as currently available treatment options. The review will be structured as responses to a series of questions, followed by a presentation of an algor...

over 10 years but were not performing well on ‘access’ because of a high number of patients who did not attend (DNA). We often had over 100 DNAs per month so many appointments were being wasted. I noticed that another local practice which permitted advance booking only 2 days ahead scored better in the ‘access’ survey than our practice. Another local practice was piloting a same day booking sys...

The use of digitalis has long been plagued by controversy. In the last few years, its efficacy in the prolonged treatment of heart failure among specific groups of patients has been questioned.' The current controversy stems from a claim by Moss et al.2 that the use of digitalis may increase mortality among infarction patients with heart failure and complex arrhythmias. Other investigators,3-5 ...

Contemporary European and American research on race, ethnicity, and health uses poorly defined labels to describe study populations. The search for accurate terminology remais controversial, for scientific and social reasons,1-16 as ilustrated by discussions of the terms Hispanic34 and Asian5 and the changing meaning of ethnicity and race in the United Kingdom" and the United States.2"2 Researc...

From the Division of Nephrology and Hypertension and the Department of Physiology and Pharmacology, Oregon Health and Science University and Veterans Affairs Medical Center, Portland, OR (D.H.E.); and the Division of Renal Diseases and Hypertension, University of Colorado Health Sciences Center, Denver (T.B.). Address reprint requests to Dr. Ellison at the Division of Nephrology and Hypertensio...