the main factors affecting pregnancy and implantation rates are uterine receptivity, embryo quality, and transfer efficiency. embryo transfer (et) is the last step of critically important procedure of in vitro fertilization (ivf) and probably the least successful step in assisted reproductive technology (art) treatment cascade; though simple in most of the cases, it may pose to be the most diff...

background: addition of amino acids to the culture medium is beneficial for embryonic development in many species. objective: the objective of this study was to investigate the effects of amino acids on the in vitro maturation and embryonic development of the bovine oocyte. materials and methods: bovine ovaries were collected from a local abattoir and brought into laboratory. cumulus-oocyte com...

background: ovarian pregnancy constitutes 0.15-3% of all ectopic pregnancies. the incidence of ectopic pregnancy is on the rise owing to evolution in assisted reproductive techniques (art). the incidence reported following in vitro fertilization (ivf) or embryo transfer (et) is 0.27% per clinical pregnancy. case: we present a case of a 13-weeks ovarian pregnancy following ivf-et and through a r...

background: supplementation of luteal phase with progesterone is prescribed for women undergoing routine ivf treatment. objective: the objective of this study was to compare the efficacy of three types of progesterone on biochemical, clinical and ongoing pregnancy rates and abortion and live birth rates. materials and methods: a prospective randomized study was performed at royan institute betw...

background: endometriosis is a common hormone-dependent gynecologic disease with a high recurrence. laparotomy or laparoscopy is the standard surgery for the large endometrioma. also, sclerotherapy is basically used to treat different diseases one of which is endometrioma. objective: the study was designed to assess the value of transvaginal ultrasound-guided ethanol sclerotherapy in patients w...

In assisted reproductive technology (ART), the pregnancy and birth rates following in vitro fertilization (IVF) attempts are still low. Recently, apoptotic markers have been suggested as new criteria for oocyte and embryo quality selection. Many studies have provided evidence that poor oocyte and embryo quality can be associated with apoptosis. The aim of this review is to summarize our current...

Approximately 10-15% of the married couples remain childless. Conventional in vitro fertilisation (IVF) has been the treatment option for most of these cases. However, it is expensive and only available to a small fraction of the infertile population. The Sindh Institute of Reproductive Medicine (SIRM), Karachi, Pakistan, has introduced a new method of IVF for the first time in Pakistan. Intrav...

The aim of this study was to assess the effects of melatonin on the in vitro maturation and fertilization of sheep oocytes, and on the in vitro culture of the embryos. Oocytes from sheep ovaries collected at the slaughterhouse were divided into four groups, two of which were treated with either 10 M (M5) or 10 M (M6) melatonin, while the other two groups served as untreated controls (C5 and C6)...

BACKGROUND In 2010, Robert Edwards was awarded the Nobel Prize in Medicine for his pioneering work in the development of in vitro fertilization, a field that has touched millions of lives across the globe. Edwards dedicated his career to helping couples overcome infertility. He first established principles of early embryo development that served as the foundation for his later work. In the 1960...