Japan has a lower incidence of vulvar squamous cell carcinoma (VSCC) than Western nations. To pin-point the reasons for this, we reviewed biopsy samples from all cases treated at Nagoya University Hospital over the past 33 years in order to investigate the background lesions for VSCC. Two of 36 VSCC patients had adjacent or coexisting lichen sclerosus (LS), 5 had squamous cell hyperplasia (SCH)...

BACKGROUND The category atypical glandular cells of undetermined significance (AGUS) occurs in about 0.5% of Papanicolaou smears. Although recent case series report a great many dysplastic, cancerous, and precancerous lesions of the cervix and endometrium associated with AGUS, little attention has been focused on this issue in primary care literature. METHODS We report a case series of 52 wom...

squamous cell carcinoma (scc) is the most common malignancy of the oral cavity. this study aims to evaluate different treatment procedures including neo-adjuvant, concurrent and adjuvant therapy in treating squamous cell carcinoma of the head and neck by a meta-analysis.the authors searched all electronic databases (medline, embase and cochrane) for all the articles published from 1970 to janua...

the larvae causing myiasis can lead extensive tissue destruction, invasion into deep tissues and secondary infec­tions. poor hygiene, low socioeconomic condition and presence of open wounds are the most important predisposing factors. this case report describes destructive wound myiasis in a 58-year-old male patient diagnosed with maxillary sinus squamous cell carcinoma who lives in a rural are...

this report is related to a female 7-year-old crossbreed sheep whose right eye had been protruded andswelling of upper eyelid was observed. routine enucleating was performed. histopathological evaluation ofeyelid revealed coincidence of two kinds of neoplasms. the first part was composed of multiple lobules ofsebocytes, which were detected as meibomian adenoma. the second section included infil...

introdouction: oral squamous cell carcinoma (oscc), the most common form of oral cancer, requires early diagnosis and suitable treatments. fascin is a protein involved in cell adhesion and is increased in expression in certain types of carcinomas. the present study was conducted to assess fascin expression in oscc using an immunohistochemical technique. materials and methods: in the present ret...

background: the most frequently mutated tumor suppressor gene found in human cancer is p53. in a normal situation, p53 is activated upon the induction of dna damage to either arrest the cell cycle or to induce apoptosis. however, when mutated, p53 is no longer able to properly accomplish these functions. the aim of this study was to investigate the expression of p53 gene in cases of skin cancer...