OBJECTIVES We sought to determine joint outcomes relative to impact level of athletic participation among school-aged children who had hemophilia and were taking prophylactic factor replacement, as well as to investigate prognostic factors for joint outcomes. METHODS School-aged boys with severe hemophilia A or B at a single center were included in the study. Clinical data on baseline joint s...

‎in this paper, using the idea of convexificators, we study boundedness and nonemptiness of lagrange multipliers satisfying the first order necessary conditions. we consider a class of nons- mooth fractional programming problems with equality, inequality constraints and an arbitrary set constraint. within this context, define generalized mangasarian-fromovitz constraint qualification and show t...

 Joint Optimization of Assortment Selection and Pricing under the Capacitated Multinomial Logit Choice Model with Product-Differentiated Price Sensitivities Ruxian Wang HP Laboratories HPL-2012-207 Multinomial Logit model; assortment optimization; multi-product price optimization Many firms face a problem to select an assortment of products and determine their prices to maximize the total prof...

Constraint programmingmodels appear inmany sciences includingmathematics, engineering and physics. These problems aim at optimizing a cost function joint with some constraints. Fuzzy constraint programming has been developed for treating uncertainty in the setting of optimization problems with vague constraints. In this paper, a new method is presented into creation fuzzy concept for set of con...

Constraint programming is an emergent technology that allows modeling and solving various problems in many areas such as artificial intelligence, computer programming, computeraided design, computer graphics, and user interfaces. In this report, we recount the recent activities of research collaboration on constraint programming conducted by the authors and other researchers in France and Japan...

The authors propose a novel spatiotemporal constraint based on shape and appearance and combine it with a level-set deformable model for left ventricle (LV) segmentation in four-dimensional gated cardiac SPECT, particularly in the presence of perfusion defects. The model incorporates appearance and shape information into a ‘soft-to-hard’ probabilistic constraint, and utilises spatiotemporal reg...

Traditional vehicle routing problems implicitly assume only one crew operates a vehicle for the entirety of its journey. However, this assumption is violated in many applications arising in humanitarian and military logistics. This paper considers a Joint Vehicle and Crew Routing and Scheduling Problem, in which crews are able to interchange vehicles, resulting in space and time interdependenci...

Based on definitions, two joint-criteria, namely, the optical-thin constraint and the energy budget constraint, are proposed to judge whether the emission nature of radio pulsars is incoherent or obligatory to be coherent. We find that the widely accepted criterion, kTB ≤ ǫ, is not a rational criterion to describe the optical-thin condition, even for the simplest case. The energy budget constra...

prosthetic joint infection (pji) is a calamitous complication with high morbidity and substantial cost. the reported incidence is low but it is probably underestimated due to the difficulty in diagnosis. pji has challenged the orthopaedic community for several years and despite all the advances in this field, it is still a real concern with immense impact on patients, and the healthcare system....