BACKGROUND Literature data show that administration of atypical antipsychotic drug, risperidone (RIS), enhances antidepressive action of fluoxetine (FLU). As antidepressive treatments also regulate immune functions, we examined whether combined administration of FLU and RIS to rats subsequently subjected to a forced swimming test (FST) modifies parameters of macrophage activity that are directl...

Orthosiphon stamineus is considered an important traditional folk medicine. In this study ethanol and aqueous extracts of O. stamineus were evaluated in vitro for their antioxidant, antimicrobial as well as for their immunomodulatory properties on human peripheral blood mononuclear cells (PBMCs). The DPPH radical scavenging method was used for the determination of antioxidant activity, while th...

The root extract and fractions of Croton zambesicus were investigated for anticancer activity against HeLa cells, DNA interaction, immunomodulatory and antileishmanial activities. The GCMS analysis of the most active fraction against HeLa cell was carried. The root extract was found to exert significant anticancer activity with the hexane fraction exhibiting the most pronounced effect. The crud...

In the present study, we aimed to analyze the antinociceptive, immunomodulatory and antipyretic activities of nymphayol were investigated in wistar rats and mice. Antinociceptive effect was evaluated by acetic acid induced writhing, formalin induced paw licking and hot-plate tests. Immunomodulatory activity was assessed by neutrophil adhesion test, humoral response to sheep red blood cells, del...

The review summarizes the data on synthesis, physicochemical properties, and biological activity of poly(1-vinyl-1,2,4-triazole) its nanocomposites with silver nanoparticles. results studying antibacterial antitumor polymers their immunomodulatory ability, toxicity, interaction body cells, as well prospects for use in development medical materials, are presented.

The immunomodulatory and antimicrobial effects of methanol extract air-dried, powdered leaves Uvaria chamae (MEUL) was evaluated in this study using standard methods. Graded doses (50 mg/kg body weight, 100 200 weight 400 weight) the were administered to winster rats. control group given dimethyl sulphoxide (DMSO). Immunomodulatory effect assessed by delayed type hypersensitivity (DTH) haemaggl...

Fig (Ficus carica L.) is a natural product that potentially can improve the immune system because it has flavonoids have potential as immunostimulants. The research aims to determine possibility of fig fruit ethanol extract an immunomodulator. Immunomodulatory activity determined by knowing macrophage phagocytosis and lymphocyte proliferation in vitro levels extract. began with extraction, then...

The alcoholic liver disease usually causes overall immunological alterations which might be attributed to hepatic disease, to ethanol action, and/or to malnourishment. In the present study, efficacy of lecithin with vitamin-B complex to treat ethanol induced immunomodulatory activity was compared with the effect of lecithin alone and tocopheryl acetate (vitamin E). Ethanol (1.6 g/kg body wt/day...