Fibronectin (FN) has been considered to be involved in the malignant transformation of cells. It was thus of interest to morphologically study the cell surface distribution of FN in various types of thyroid neoplasms employing immunohistochemical techniques. Immunohistochemical staining using the specific anti-human FN antibody was performed by the avidin-biotin-peroxidase complex procedure. Co...

BACKGROUND Epstein-Barr virus (EBV) is associated with various lymphoproliferative disorders and nasopharyngeal carcinoma. Recently, some gastric cancer cells were observed to contain the EBV sequence. We detected EBV in gastric cancer by using PCR to determine the frequency of EBV-associated gastric cancer, and performed immunohistochemical staining for the latent membrane protein (LMP1), p53 ...

Same-day turnaround of pathology specimens is desirable in this era of managed care, and rapid microwave tissue processing produces histologic features of a quality equivalent to overnight processing. We studied whether microwave-assisted rapid tissue processing adversely affects the quality of immunohistochemical staining. We selected 30 specimens (20 neoplastic and 10 nonneoplastic) from our ...

This article presents the construction of scaffolds composed polylactic acid (PLA) with different concentrations hydroxyapatite (HA) by electrospinning, which were superficially modified polypyrrole (PPy/I) plasma polymerization. A preliminary study was conducted biological and mechanical behavior when they implanted in back rabbits for 30 days; bone cells differentiated from mesenchymal stem (...

Abstract Galactoceles are benign lesions formed at the expense of breast glandular tissue. Its occurrence in boys is exceptional, with isolated reports scientific literature. We present case a 2-year-old boy who debuted unilateral enlargement 18 months evolution, no other associated symptoms. Initial hormonal study showed alterations. Ultrasonography presence homogeneous 5-cm retroareolar cyst....

PURPOSE To analyze the outcomes of chemoradiotherapy for extrahepatic bile duct (EHBD) cancer patients who underwent R2 resection or bypass surgery and to identify prognostic factors affecting clinical outcomes, especially in terms of molecular biomarkers. MATERIALS AND METHODS Medical records of 21 patients with EHBD cancer who underwent R2 resection or bypass surgery followed by chemoradiot...

The immunohistochemical (IHC) staining of the human epidermal growth factor receptor 2 (HER2) biomarker is widely practiced in breast tissue analysis, preclinical studies, and diagnostic decisions, guiding cancer treatment investigation pathogenesis. HER2 demands laborious chemical processing performed by a histotechnologist, which typically takes one day to prepare laboratory, increasing analy...