نتایج جستجو برای: immune protection

تعداد نتایج: 434794  

Journal: :Clinical and vaccine immunology : CVI 2013
Gilbert J Kersh Kelly A Fitzpatrick Joshua S Self Brad J Biggerstaff Robert F Massung

Q fever is a zoonotic disease caused by infection with the bacterium Coxiella burnetii. Infection with C. burnetii results in humoral and cellular immune responses, both of which are thought to contribute to protection against subsequent infection. Whole-cell formalin-inactivated vaccines have also been shown to induce both humoral and cellular immunity and provide protection. Whether measureme...

Journal: :Journal of virology 2001
M Gupta S Mahanty M Bray R Ahmed P E Rollin

Ebola hemorrhagic fever is a severe, usually fatal illness caused by Ebola virus, a member of the filovirus family. The use of nonhomologous immune serum in animal studies and blood from survivors in two anecdotal reports of Ebola hemorrhagic fever in humans has shown promise, but the efficacy of these treatments has not been demonstrated definitively. We have evaluated the protective efficacy ...

2016
Igor Golovliov Helena Lindgren Kjell Eneslätt Wayne Conlan Amandine Mosnier Thomas Henry Anders Sjöstedt

Francisella tularensis is a highly virulent intracellular bacterium and cell-mediated immunity is critical for protection, but mechanisms of protection against highly virulent variants, such as the prototypic strain F. tularensis strain SCHU S4, are poorly understood. To this end, we established a co-culture system, based on splenocytes from naïve, or immunized mice and in vitro infected bone m...

Journal: :Virology 1998
L A Morrison X J Da Costa D M Knipe

Herpes simplex virus (HSV) most frequently initiates infection at a mucosal surface; thus mucosal immune responses are likely to be important in defense against HSV infection. We have examined the effects of eliciting mucosal as well as systemic immune responses on protection against genital challenge infection with virulent HSV-2 in mice immunized with a replication-defective mutant of HSV-2. ...

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