نتایج جستجو برای: immune cells
تعداد نتایج: 1545612 فیلتر نتایج به سال:
objective: the present study examines the effects of increased heat shock proteins expression in mda-mb468 adeno-carcinoma cells on expansion and differentiation of hematopoetic stem cells from human umbilical cord blood. materials and methods: highly purified human cd34+ cells (magnetic bead isolation) derived from umbilical cord blood were cultured, under three conditions, in the presence of ...
The incidence of obesity, as a major health problem, has increased significantly over the past decades. This condition is associated with an increased risk of cancers, type 2 diabetes, and cardiovascular diseases. The current study aimed to investigate the effects of inflammation and changes of adipose tissue-resident immune cells on increasing the risk of cancer in obese individuals. In obesit...
dendritic cells (dcs) are professional antigen presenting cells that have a potential role in the initiating of immune responses. the cell vaccination is a new strategy in treatment of infectious diseases and cancers. in this study, we have generated monocyte-derived dendritic cells of lymphoma patient's peripheral blood mononuclear cells then; these cells were used as vaccine in lymphoma patie...
Abstract Glioblastoma is the most frequent and malignant brain tumor. Immune therapies have had limited effect, but not much known about frequency type of immune cells in infiltration zone periphery. In these areas, tumor migrate into parenchyma prevent total resection thereby leading to recurrence. This study aims quantify distribution glioblastomas. A cohort 67 glioblastomas was established c...
Background & Objective: Dendritic cells(DCs) play an important role in directing immune response toward TH1(T-Helper 1) or TH2(T-Helper 2). These cells may induce distinct cytokine patterns in different tissues. So the pattern of cytokine induction by liver and spleen DCs may differ from each other. To investigate the difference between immune responses in the liver(as a non-lymphoid organ ...
CD8+ T cells are thought to play an important role in protective immunity to tuberculosis. The major histocompatibility complex class I subtype HLA-A*0201 is one of the most prevalent class I alleles, with a frequency of over 30% in most populations. HLA-A*0201 transgenic, H-2Db/mouse beta2-microglobulin double-knockout mice (HHD) which express human HLA-A*0201 but no mouse class I, was shown t...
unresponsiveness to hepatitis b surface antigen (hbsag) has been shown to be associated with dysfunction of the presenting cells (apc) and defect in the specific b-lymphocyte and/or t-lymphocyte repertoires. direct determination of the frequency of specific t-lymphocytes together with complementary analysis of the naive circulating immune cells could provide valuable information about the cel...
Background and purpose: CD4+CD25+FOXP3+ regulatory T cells (CD4+CD25+FOXP3+ Tregs) are a group of T lymphocytes that play an important role in regulating immune system responses by suppressing the activity of other T cells and establishing homeostasis in the immune system. Th1 and Th2 cells are other groups of CD4+ cells that play important functions in inducing inflammatory immune responses. C...
objectives the cause of rheumatoid arthritis (ra) as a chronic inflammatory autoimmune disease is still unknown. it appears that both genetic and environmental factors play a role in its pathogenesis. recent studies reveal that in addition to the cns, immune cells synthesis neurotransmitters so that these catecholamines can regulate immune functions. the aim of this study is to evaluate the dop...
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