There have been various obstacles to investigating the immediate type of spontaneous hypersensitivity in man. These have included the lack of in vitro methods of measuring allergic antibody and a limitation on the types of investigations that can be done in man without risk. Models of hypersensitivity using immunized animals have not involved antibody of the type occurring in spontaneous allerg...

objective: an immediate complete denture is fabricated before the extraction of all teeth. it has several advantages such as preservation of esthetics, muscular tone, normal speech and reduction of post-operative pain. this report describes a method of using patient’s current fixed partial denture (fpd) for single-appointment construction of interim immediate denture.   case: we used patient’s ...

Penetration of the gut epithelial barrier by intact luminal antigen is necessary for immunologically mediated pathophysiology in the context of food allergy. We investigated if glucagon-like peptide-2 (GLP-2) could affect immediate hypersensitivity and late-phase allergic inflammation in a murine model. Mice were sensitized to horseradish peroxidase (HRP); studies were conducted 14 days later. ...

Betalactam (BL) antibiotics are the most common cause of drug-induced hypersensitivity reactions (DHR). We present 2 clinical cases patients with suspected immediate BL DHR who underwent drug allergy workup according to standardized diagnostic procedures, including skin tests (STs: prick, prick test, and intradermal [IDTs]) provocation (DPTs).1 ST results became positive after first DPT dose. T...

conclusions the characteristic features of ige-mediated food allergy are abrupt onset of clinical symptoms, which may result in a life-threatening events, and positive results of the majority of the paraclinical tests that mainly trace the specific ige to foods. moreover, non–ige-mediated food allergies present as chronic diseases and due to lack of proper diagnostic tests the similarity of the...

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BACKGROUND We previously reported perfect specificity and low sensitivity of skin tests in proton pump inhibitor (PPI)-induced immediate hypersensitivity reactions in a prospective multicenter study. Here, in a retrospective study, we aimed to further evaluate the diagnostic workup procedures and characteristics of the patients with suspected PPI hypersensitivity. METHODS This national multic...

OBJECTIVE To discuss the pathophysiology of vancomycin-induced immediate hypersensitivity reactions, review the process of vancomycin desensitization, and provide specific directions for ordering and preparing rapid and slow desensitization protocols. DATA SOURCES A MEDLINE search (1966-February 2001) of English-language literature pertaining to vancomycin desensitization and hypersensitivity...

1. Van Thiel PH. The final hosts of the herringworm Anisakis marina. Trop Geogr. Med 1966; 18:310-328. 2. Kasuya S, Hamano H, Izumi S. Mackerel induced urticaria and Anisakis. Lancet 1990; 335: 665. 3. Audicana MT, Fernández de Corres L, Muñoz D, et al. Anisakis simplex a new sea-food allergen. Allergy. 1995; 50(sup 26): 127. 4. Kassai T, Cordero del Campillo M, Euzeby J, Gaafar S, Hiepe T, Him...

Soluble antigen was prepared from adult worms and microfilariae of Onchocerca volvulus. In 27 patients clinically characterized as having generalized type (17) and localized reaction type (10) onchocerciasis, the response to this antigen was assessed in vivo by skin testing and in vitro by leucocyte migration inhibition assay. Three varieties of skin hypersensitivity were observed: Immediate, A...