Microalgae have been widely recognized as promising hosts for production of various valuable compounds. However, low expression or silencing transgenes in most microalgae species hindered their broader implementation biotechnological applications. In many eukaryotes, intron mediated enhancement (IME) gene by inclusion introns heterologous sequences has resulted a significant increase transgene ...

A measure known as inspection time (IT) has been shown to account for approximately 25% of the variance in peoples’ intellectual abilities, as measured by IQ. Despite this strong relationship, inspection time has had only limited success in expanding our knowledge regarding the nature of intelligence, which can be attributed to a lack of understanding of the neurophysiology underlying IT. In th...

One of the most interesting scientific developments during the next two decades will be the unraveling of the structure of computation in living organisms. Since the information processing capabilities of living organisms are in many aspects superior to those of our current artificial computing machinery, this is likely to have significant consequences for the way in which computers and robots ...

In this extended abstract back-and-forth structures are defined and applied to the semantics of natural language. Back-and-forth structures consist of an event structure and an interval structure communicating via a relational link; transitions in the one structure correspond to transitions in the other. Such structures enable us to view temporal constructions (such as tense, aspect, and tempor...

An average-time game is played on the infinite graph of configurations of a finite timed automaton. The two players, Min and Max, construct an infinite run of the automaton by taking turns to perform a timed transition. Player Min wants to minimize the average time per transition and player Max wants to maximize it. A solution of average-time games is presented using a reduction to average-pric...

Structured Abstract In this paper, we describe the participation and results of CAUVIS-IME-USP at TRECVID 2011 in instance search pilot task. Briefly, what approach or combination of approaches did you test in each of your submitted runs?  CAUVIS_USP: PHOW descriptor and the bag-of-word approach. What if any significant differences (in terms of what measures) did you find among runs? We submit...

BACKGROUND Much implementation research is focused on full-scale trials with little evidence of preceding modelling work. The Medical Research Council Framework for developing and evaluating complex interventions has argued for more and better theoretical and exploratory work prior to a trial as a means of improving intervention development. Intervention modelling experiments (IMEs) are a way o...

The predictability of the computation t ime of program modules is very important f o r estimating an accurate worst-case execution t ime ( W C E T ) of a task in real-time systems. Dynamic storage allocation ( D S A ) is a common programming technique. Although many DSA algorithms have been developed, they focus o n the average execution t ime rather than the W C E T , making it is very dif icu...

Meiosis is a highly regulated process in eukaryotic species. The filamentous fungus Neurospora crassa has been shown to be missing homologs of a number of meiotic initiation genes conserved in Saccharomyces cerevisiae, but has three homologs of the well-characterized middle meiotic transcriptional regulator NDT80. In this study, we evaluated the role of all three NDT80 homologs in the formation...