A few tumours are exceptionally stubborn to oral chemotherapy. The endurance of in a cases is helped by checkpoint immunomodulation keep up the unevenness between resistant reconnaissance and disease cell division.

Chauhan, R.S.; Singh, B.P. and Singh, L.K. 2001. Immunomodulation with Kamdhenu ark in mice. J. Immunol. Immunopathol., 3: 74-77. The immunomodulatory effect of Kamdhenu ark was studied on 20 mice divided into 2 groups. Groups I was kept as control while group II mice were given 1 ml Kamdhenu ark in water for a period of 90 days. Results indicated that there was increased Band Tlymphocyte blast...

Background: Gut microbiota play an important role in the inflammation. This study aimed to investigate whether exogenous probiotics could improve intestinal barrier function effect via attenuating inflammation and immunomodulation clinical outcomes critically ill patients.

Despite the advances of microbiology, immunology and pharmacology, tuberculosis (TB) remains a serious public health problem, particularly in poor countries. Portugal, which has reduced the incidence of the disease in 2009, had an incidence of new cases of about 27.0 per 100,000 inhabitants, a figure which surpasses the average in Europe (15/100,000 inhabitants) and also values considered of lo...

Immunomodulators, modify the activity of immune function through the impulsive modulation of informational molecules such as cytokines. This may propose an explanation of the effects of herbs on the immune system and other tissues. The immune system is a part of body to find the pathogen by using a specific receptor to create instantly response by the activation of immune components cells, cyto...

Interleukin (IL)-18 is a cytokine with a broad array of effector functions, the most prominent of which is to act synergistically with IL-12 in interferon-Á production and the induction of a strong T-helper-1-mediated immune response. In addition, IL-18 also upregulates the production of proinflammatory cytokines such as IL-1 and tumor necrosis factor-·. Analysis of IL-18-deficient mice reveale...

bacterial protein toxins have been exploited as therapeutic agents and as vaccines. an issue of deserving interest is development of new generations of vaccines and immune adjuvants. in this study an active assembled recombinant shiga toxin of escherichia coli (rstx1) and its derivatives, recombinant a and b subunits (stx1-a and stx1-b), were used to immunize mice. the elicited antibody respons...