حي ت يو جذومنلأا ىلع يطخلا ريغ أ ،ءاملا ةمدص رث جاوملأاو يلاقتنلاا ه ، ةفاضإ ىلإ ضيف ءا ملا . مب ا نمق ه تءافآو ما ظنلا ة ناتم ة ساردلو أ ة شقان تاز يمملاو تابارط ضلاا ر ث (Parameters) ملا ر يغت ة بُ لطتيو ، مُيم صت ةَ فرعم ما ظنلا اذ ه ي ف ر يغتلا ىد م هذ ه مي ق تازيمملا . ةُقيرط تمدخُتسا دقو H ∞ يف دودحلا ةد يدع ميمصتلا . تا نارتقلاا را بتخا م ت ا مآ لا ة يكيمانيدلا ة ننقملا مكحت لل ة بولطملا ...

Non-radioisotopic local lymph node assay (LLNA) employing 5-bromo-2'-deoxyuridine (BrdU) with flow cytometry (FACS) or immunohistochemistry (IHC) is gaining attention due to a regulatory issue of using radioisotope, (3)H-thymidine, in vivo in traditional LLNA. In this study, to compare the performance of these non-radioisotopic endpoints, 7 chemicals with known sensitizing potencies were examin...

Tissue microarray (TMA) is a high throughput analysis tool to identify new diagnostic and prognostic markers in human cancers. However, standard automated method in tumour detection on both routine histochemical and immunohistochemistry (IHC) images is under developed. This paper presents a robust automated tumour cell segmentation model which can be applied to both routine histochemical tissue...

BACKGROUND Helicobacter pylori, which is associated with many upper gastrointestinal diseases, is found in half of the population of the world. Several special stains and immunohistochemistry stain for H. pylori are available. The need for and usefulness of immunohistochemical (IHC) technique has been debated for years. Toluidine blue is a simple stain for microbiological studies and is easily ...

Tissue transglutaminase 2 enzyme plays a diverse role in intracellular and extracellular functioning. Aberrant expression of anti-TG2 antibody has recently been proposed for extraintestinal identification of celiac disease (CeD), but its utility is questionable. To examine whether anti-TG2 immunohistochemical (IHC) staining can be of diagnostic value in identifying extraintestinal involvement i...

The literature acknowledges difficulties in diagnosing cervical intraepithelial neoplasia (CIN) when it is closely associated with a dense chronic inflammatory infiltrate within the superficial cervical stroma. This is due to atypical reactive and regenerative epithelial changes such as nuclear enlargement/overlap and impaired maturation, mimicking some of the cytological and architectural feat...

The literature acknowledges difficulties in diagnosing cervical intraepithelial neoplasia (CIN) when it is closely associated with a dense chronic inflammatory infiltrate within the superficial cervical stroma. This is due to atypical reactive and regenerative epithelial changes such as nuclear enlargement/overlap and impaired maturation, mimicking some of the cytological and architectural feat...

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Page 1 Feb.2011 20/20 GeneSystems, Inc. The need for multiplex detection of tissue biomarkers. There is an ever growing demand for increased biomarker analysis in human tissue specimens. Analysis of tissue biomarkers is key to understanding the activation status of particular pathways in specific cell types and can be indicative of disease diagnosis, prognosis, and prediction of therapeutic eff...