Let S be a symmetric monoidal category with product ⊗ and unit object κ. Definition 1. An operad C in S consists of objects C (j), j ≥ 0, a unit map η : κ → C (1), a right action by the symmetric group Σj on C (j) for each j, and product maps γ : C (k)⊗ C (j1)⊗ · · · ⊗ C (jk) → C (j) for k ≥ 1 and js ≥ 0, where ∑ js = j. The γ are required to be associative, unital, and equivariant in the follo...

The digitization thrust on high-value manufacturing and services opens up new opportunities for ensuring total system uptime, reliability, efficiency particularly mission-critical assets. process evolves intelligent systems (IMS) which transforms maintenance into predictive reliability achieving consistent quality throughout process. This article unveils the grinding (IGS) challenging applicati...

The immune response of jawed vertebrates is an inducible, highly specific defense mechanism that is characterized by an enormous diversity in recognition capacity. This allows responses to potential pathogens that have never been previously encountered in the evolution of the species. The molecules that carry out the specific recognition of antigen are glycoproteins termed immunoglobulins (Igs)...

This paper presents 3DCoffee@igs, a web-based tool dedicated to the computation of high-quality multiple sequence alignments (MSAs). 3D-Coffee makes it possible to mix protein sequences and structures in order to increase the accuracy of the alignments. Structures can be either provided as PDB identifiers or directly uploaded into the server. Given a set of sequences and structures, pairs of st...

Since 1994 the International GPS Service (IGS) has provided precise GPS orbit products to the scientific community with increased precision and timeliness. Many national geodetic agencies and GPS users interested in geodetic positioning have adopted the IGS precise orbits to achieve centimeter level accuracy and ensure long-term reference frame stability. Relative positioning approach that requ...

The immunoglobulins (Igs), proteins produced by B lymphocytes, have been extensively studied both at molecular and genetic levels. They consist of two identical heavy chains and two identical light chains having therefore the same isotype and the same type, respectively. Igs are puriRed for three main purposes. (i) as therapeutic injections to patients; (ii) for use as a tool in research or cli...

INTRODUCTION The identification of specific targets for treatment of ovarian cancer patients remains a challenge. The objective of this study is the analysis of oncogenic pathways in ovarian cancer and their relation with clinical outcome. METHODOLOGY A meta-analysis of 6 gene expression datasets was done for oncogenic pathway activation scores: AKT, β-Catenin, BRCA, E2F1, EGFR, ER, HER2, INF...

In this study, the role of Igs in the recognition and removal of oxidatively damaged human red blood cells (RBCs) was investigated. Phagocytosis of normal RBCs exposed to the oxidative hemolytic agent phenylhydrazine (Phz) and of glucose-6-phosphate dehydrogenase (G6PD)-deficient RBCs by murine macrophages was examined. A 40-fold increase in phagocytosis of RBCs treated with 3 mmol/L Phz was ob...