This paper investigates sudden changes in volatility in the stock markets of new European Union (EU) members by utilizing the iterated cumulative sums of squares (ICSS) algorithm. Using weekly data over the sample period 1994–2006, the time period of sudden change in variance of returns and the length of this variance shift are detected. A sudden change in volatility seems to arise from the evo...

BACKGROUND The International Carotid Stenting Study (ICSS) of stenting and endarterectomy for symptomatic carotid stenosis found a higher incidence of stroke within 30 days of stenting compared with endarterectomy. We aimed to compare the rate of ischaemic brain injury detectable on MRI between the two groups. METHODS Patients with recently symptomatic carotid artery stenosis enrolled in ICSS...

Over 100 years ago, George Bernard Shaw, speaking through his protagonists, weapons manufacturer Andrew Undershaft and Undershaft’s daughter Salvation Army Major Barbara, explored the uneasy relationship that existed, and exists still, between ill-gotten gains and the public good. Now, a century later, a similar uneasy relationship exists. But this time it is not cannons versus religion, but to...

Information and communication systems (ICSs) must comply with increasingly stringent requirements to ensure the reliability speed of information transmission, noise immunity, security. This paper reports methods synthesize discrete complex cryptographic signals, underlying construction which are random (pseudo-random) processes; for synthesizing characteristic signals whose is based on using na...

OBJECTIVE Inadequate asthma control may affect asthma resource use and treatment charges, consequently contributing to the growing economic burden of asthma. The study objective was to determine the impact of medication adherence and asthma control on resource use and charges in mild asthmatic patients treated with inhaled corticosteroids (ICSs). RESEARCH DESIGN AND METHODS A claims database ...

Asthma management guidelines emphasize the importance of effective treatment to achieve and maintain control of asthma. However, despite widely available and effective treatments, achieving control of asthma is still an unmet need for many patients. Adding a second bronchodilator with a different mechanism of action for the treatment of uncontrolled asthma can be a suitable therapeutic approach...

BACKGROUND While the optimal management of early breast cancer patients with sentinel lymph node (SLN) involvement mapped in the internal thoracic chain is still debated, biopsy may be performed when surgeons select patients who are most likely to benefit. The aim of this study is to examine anatomical aspects of internal thoracic nodes (ITNs) to orientate SLN biopsy in the parasternal area. ...

Absolute differential cross sections (DCSs) for electron interaction with BF3 molecules have been measured in the impact energy range of 1.5-200 eV and recorded over a scattering angle range of 15°-150°. These angular distributions have been normalized by reference to the elastic DCSs of the He atom and integrated by employing a modified phase shift analysis procedure to generate integral cross...

Several preclinical studies indicate that selective kappa-opioid receptor (KOR) antagonists have antidepressant-like effects, whereas KOR agonists have opposite effects, suggesting that each might be useful in the treatment of mood abnormalities. Salvinorin A (salvA) is a valuable KOR agonist for further study due to its high potency and receptor selectivity. However, it has short lasting effec...