نتایج جستجو برای: ich
تعداد نتایج: 7722 فیلتر نتایج به سال:
BACKGROUND AND PURPOSE The aim of the present study was to investigate the effects of normobaric oxygen (NBO) therapy on T2*-weighted images of intracranial hemorrhages (ICHs). METHODS Two common models of ICH were performed in mice, and longitudinal T2*-weighted images of the hematomas were acquired under normoxia or NBO. The effects of NBO were also investigated on perfusion-weighted imagin...
Silent information regulator 1 (SIRT1) exerts neuroprotection in many neurodegenerative diseases. However, it is not clear if SIRT1 has protective effects after intracerebral hemorrhage (ICH)-induced brain injury in rats. Thus, our goal was to examine the influence of SIRT1 on ICH injuries and any underlying mechanisms of this influence. Brain injury was induced by autologous arterial blood (60...
Inflammation and immunity play a crucial role in the pathogenesis of Intracerebral hemorrhage (ICH). Toll-like receptor 4- (TLR4-) mediated nuclear factor kappa-B (NFkappaB) signaling plays critical roles in the activation and regulation of inflammatory responses in injured brain. However, the involvement of TLR4-mediated NFkappaB signaling in the pathogenesis of ICH remains unknown. The presen...
Infiltration of neutrophils has been suggested to play an important role in the pathogenesis of intracerebral hemorrhage (ICH) for which effective therapeutic interventions remain unavailable. In the present study we focused on leukotriene B4 (LTB4) as a potent chemotactic factor for neutrophils in order to address its contribution to the pathologic events associated with ICH. ICH with hematoma...
Comparison of ABC/2 with the Simplified ABC/2 Formula in Calculating Intracerebral Hemorrhage Volume
Background: Bedside ABC/2 methods of measuring intracerebral hemorrhage (ICH) volumes are valuable clinical and research tools. The two most common methods of bedside calculation are the ABC/2 formula and the sABC/2 formula. Methods: We retrospectively reviewed 142 consecutive spontaneous ICH patients admitted to our institution from November 1, 2009 to October 1, 2010. ICH volume was calculate...
Novel oral anticoagulants (NOACs) reduce incidence of stroke and intracerebral hemorrhage (ICH) in patients with nonvalvular atrial fibrillation. Several studies demonstrated hematoma expansion in patients with ICH occurring during warfarin therapy and poor clinical outcomes. However, information regarding hematoma size, its expansion, and functional and vital outcomes of patients with ICH occu...
Ich versichere hiermit ehrenwörtlich, dass die vorgelegte Dissertation von mir selbständig und ohne unerlaubte Hilfe angefertigt wurde. Erklärung Hiermit erkläre ich, dass ich mich nicht anderweitig einer Doktorprüfung ohne Erfolg unterzogen habe.
OBJECTIVE To investigate whether cortical superficial siderosis (cSS) is associated with increased risk of future first-ever symptomatic lobar intracerebral hemorrhage (ICH) in patients with cerebral amyloid angiopathy (CAA) presenting with neurologic symptoms and without ICH. METHODS Consecutive patients meeting modified Boston criteria for probable CAA in the absence of ICH from a single-ce...
INTRODUCTION Evaluation recommendations for patients on anticoagulant and antiplatelet (ACAP) therapy that present after mild traumatic brain injury (TBI) are controversial. At our institution, an initial noncontrast head computed tomography (HCT) is performed, with a subsequent HCT performed six hours later to exclude delayed intracranial hemorrhage (ICH). This study was performed to evaluate ...
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