There are many cases of smelling disorders, which can impact an individual’s ability to smell. In addition, it’s important to understand there is a whole population among us who cannot smell (anosmia), who may have grown up never smelling (congenital anosmia), or who have reduced smell (hyposmia). Because the sense of smell is not as severe, life-threatening, or well-known, it is not widely stu...

Clinical olfactory tests are used to address hyposmia/anosmia levels in patients with different types of olfactory impairments. Typically, a given test is employed clinically and then replaced by a new one after a certain period of use which can range from days to several months. There is a need to assess control quality of these tests and also for a procedure to quantify their degradation over...

INTRODUCTION Since the discovery of the first documented case of Paecilomyces in 1963, only five cases of Paecilomyces sinusitis have been described to date and all of them have predisposing factors such as immunocompromised status or prior nasal surgery. We present the first case of Paecilomyces lilacinus sinusitis in a fit young woman with no identified predisposing factors. To the best of ou...

Background Lesions of the sinonasal area are varied, but they mostly present as polypoid masses which require meticulous work-up to reach at the most probable diagnosis. Objective Analysis of polypoid sinonasal masses in terms of etiology, clinical presentations, brief demographic profile, clinico-histologic correlate where possible, and follow-up results. Method In this descriptive, longitudin...

The establishment of normal olfactory function by means of a simple and reliable test is one method that could minimize olfactory test procedures in the clinic. This retrospective study analyzed the identification of 16 odors by 613 subjects (aged 18-96 years, 266 men) as a part of a complex olfactory test battery by which 183, 251, and 179 subjects were diagnosed with anosmia, hyposmia, or nor...

While the contributing role of testosterone to bone health is rather modest compared to other factors such as estradiol levels, male hypogonadism is associated with low bone mass and fragility fractures. Along with stimulating physical puberty by achieving virilization and a normal muscle mass and improving psychosocial wellbeing, the goals of testosterone replacement therapy in male hypogonadi...

Recent clinical and experimental studies suggest that zinc deficiency may play an important role in the pathogenesis of (1) acrodermatitis enteropathica, and in certain cases of (2) hypogonadal dwarfism, (3) congenital malformations, (4) hypogeusia and hyposmia, (5) nyctalopia and (6) impaired wound healing. Distrubances of zinc metabolism also occur in a broad spectrum of other clinical disord...

Schwannomas are most commonly located on the VIII CN(80%). They are more rarely found in the nasal region (4%). On the nose, they may rise from the autonomous nervous fibers or from branches of the V CN. Malignant transformation is rare (2%). According to Hillstrom1, electron microscopy and immunohistochemistry help in differentiating this tumor from neurofibromas, the latter with more common m...

Abnormalities of taste and smell were studied in 29 patients after head trauma. These abnormalities included decreased taste acuity (hypogeusia), a distortion of taste acuity (dysgeusia), decreased smell acuity (hyposmia), and a distortion of smell acuity (dysosmia). This syndrome can occur even after minimal head trauma and can begin months after the moment of injury. The patients exhibited a ...

BACKGROUND Olfaction has been demonstrated to have a great impact on patients' lives. Transsphenoidal endoscopic pituitary surgery is associated with potentially significant damage to olfactory tissues, but to date this issue has been only poorly documented in the literature. STUDY DESIGN Prospective cohort study comparing olfactory outcomes pre- and postpituitary surgery. METHOD Patients w...