BACKGROUND Oxygen supply as a lifesaving intervention is frequently used to treat preterm infants suffering additionally from possible prenatal or perinatal pathogen features. The impact of oxygen and/or physical lung injury may influence the morphological lung development, leading to a chronic postnatal lung disease called bronchopulmonary dysplasia (BPD). At present different experimental BPD...

Backgrounds: We studied the changes in blood-brain barrier (BBB) permeability and brain trace elements concentration in acute hypo-osmolality and pentylenetetrazol (PTZ)-induced seizures model in rats. Furthermore, the effect of acute hypo-osmolality on seizure activity (patterns) in the PTZ model, the correlation between seizure severity score (SS score) and changes of both of BBB permeability...

The concept of hypo-Euclidean norm for an n−tuple of vectors in inner product spaces is introduced. Its fundamental properties are established. Upper bounds via the BoasBellman [1]-[3] and Bombieri [2] type inequalities are provided. Applications for n−tuples of bounded linear operators defined on Hilbert spaces are also given.

Abstract BACKGROUND AND OBJECTIVES The role of stereotactic radiosurgery (SRS) for patients with brain metastases from colorectal cancers (CRC) has not been established. authors present a single-institution experience CRC who underwent SRS metastatic spread. METHODS We retrospectively analyzed 112 (64 female, 57.14%) 450 that were treated Gamma Knife between 2000-2022. median age at was 63 year...

heparin was isolated from whole clam tissue marcia opima . purification of multimilligram quantities of heparin from this tissue sample permitted a thorough examination of its anticoagulant activity characterization, which was partially purified by fractionation by anion exchange chromatography using deae cellulose column. the isolated crude and partially purified fractionated sample showed met...

OBJECTIVE One third of patients with a major depressive episode also experience manic symptoms or, even, a (hypo)manic episode. Retrospective studies on the temporal sequencing of symptomatology suggest that the majority of these patients report depressive symptoms before the onset of manic symptoms. However, prospective studies are scarce and this study will, therefore, prospectively examine t...

PURPOSE This study investigated the efficacy of an intermittent critical power (CP) model, termed the "work-balance" (W'BAL) model, during high-intensity exercise in hypoxia (HYPO). METHODS Eleven trained male cyclists (mean ± SD age, 27 ± 6.6 yr; V˙O2peak, 4.79 ± 0.56 L·min(-1)) completed a maximal ramp test and a 3-min "all-out" test to determine CP and work performed above CP (W'). On anot...

The term "immune privilege" was coined to describe weak immunogenicity (hypo-immunity) that manifests in some transplant settings. We extended this concept to encompass hypo-immunity that manifests at local sites of inflammation relevant to clinical diseases. Here, we focus on emerging evidence that enhanced tryptophan catabolism is a key metabolic process that promotes and sustains induced imm...

Pre-exercise carbohydrate feeding may result in rebound hypoglycemia in some but not all athletes. The aim of the present study was to examine whether insulin sensitivity in athletes who develop rebound hypoglycemia is higher compared with those who do not show rebound hypoglycemia. Twenty trained athletes (VO(2max) of 61.8 +/- 1.4 ml.kg(-1).min(-1)) performed an exercise trial on a cycle ergom...