Abstract Introduction During the COVID-19 pandemic, vitamin D was used along with C and zinc as a preventive curative therapy against SARS-CoV-2 infection. Vitamin toxicity, even if it is rare, occurs when serum concentrations exceed 150 ng/mL usually manifested by hypercalcemia phenomena. Case report We hereby case of two twin sisters who self-medicated in dose 4 × 4,000 IU/day for almost 10 m...

Erythrocytes from rats fed large doses of Vitamin A alone, or large doses of vitamin A and vitamin E or diphenyl-p-phenylene diamine (DPPD) were studied for H2O2-induced hemolysis. The vitamin A-dosed rats were more susceptible than normal rats to H2O2-induced hemolysis. Hemolysis was not accompanied by lipid peroxidation. Nevertheless, the antioxidants vitamin E and DPPD inhibited hemolysis in...

BROWN AND SHOHL [1930] and Watchorn [1930] have shown that large doses of irradiated ergosterol lead to a decreased retention of calcium in rats, in spite of the calcification of certain tissues which takes place at the same time. It has been noted also by Brown and Shohl [1930], Duguid, Duggan and Gough [1930] and by Harris [1930] that the severity of the symptoms of hypervitaminosis D corresp...

OBJECTIVE Vitamin D is a fat-soluble secosteroid hormone that regulates calcium, magnesium, and phosphate homeostasis and plays a pivotal role as antiproliferative and immunomodulatory mediator. Considering the different sources of synthesis and dietary intake as well as the pleiotropic actions in extremely diverse (micro)environments of the body, the supplementation of this Vitamin should be c...

Vitamin D is a fat-soluble steroid hormone that is crucial for human health and has recently generated controversy regarding its role in human health and disease. In this Special Article, we discuss our dermatologic perspective on vitamin D in a question-and-answer format. We discuss methods of obtaining vitamin D, including cutaneous photobiosynthesis, diet, and supplements and include the rec...

Hypercalcaemia is a recognised complication of hypothyroidism. We describe three patients who developed hypercalcaemia after thyroidectomy when thyroid supplements were discontinued. They were treated with thyroxine, dihydrotachysterol, and calcium after operation, and in all three cases serum calcium concentrations remained constant during combined treatment. Thyroxine treatment was discontinu...