Background: Psoriasis is a chronic inflammatory dermatosis. The hyperproliferation and hyperkeratosis of keratinocytes key step in the pathogenesis psoriasis. Long non-coding RNAs (lncRNAs) mRNAs regulate gene expression various biological process, including function keratinocytes. This research investigated profile lncRNAs patients with psoriasis vulgaris.

The aim of this study was to determine the expression intensity of c-erbB-2 antigen in oral lichen planus and erosive form of oral lichen in 30 patients, and to compare the obtained results with the inflammation intensity i.e. hyperkeratosis. The examination of expression intensity of c-erbB-2 antigen was conducted through immunohistochemical analysis by APAAP method. Obtained reaction of exami...

Crusted scabies (CS) is a very contagious rare skin infestation caused by Sarcoptes scabiei var hominis, an obligate human parasite, transmitted by skin-to-skin contact.1 Clinically, it can present with psoriasiform skin lesions in acral distribution with variable whitish scaling. It usually involves the subungueal area with nail hyperkeratosis and dystrophy.2 A 56-year-old man, alcoholic, pres...

In this study, a Vohwinkel syndrome case is presented where in 5th digit constriction bands in the right hand were reconstructed using a distant abdominal skin flap. Vohwinkel syndrome, or keratoderma hereditarium mutilans, is a rare, autosomal dominant genetic skin condition that causes palmoplantar hyperkeratosis and constricts finger and/or toe bands. In a typical manifestation, the finger a...

Actinic keratosis (AK) lesions are surrounded by field cancerization (areas of subclinical, non-visible sun damage). Existing AK grading tools rely on AK counts, which are not reproducible. An Actinic Keratosis Field Assessment Scale (AK-FAS) for grading the severity of AK/field was developed. Standardized photographs of patients representing the full range of AK severity were collected. Six in...

Many people living in developing countries still prefer to sit on the carpet or uncarpeted floor, and many times they sit in a cross legged position. Continuous rubbing and friction of the ankles over the carpet or the plain hard surface may cause callosity of the ankles. This can cause a cosmetic problem. We describe a case series of ankle hyperkeratosis referred to our outpatient clinic in Ah...

A 9-year old boy had severe muscle weakness and typical skin rash and EMG with diagnosis of dermatomyositis associated with erythrodermia with islands of normal skin and palmoplantar hyperkeratosis, which was reported. As PRP in skin biopsy. Association dermatomyositis with PRP is very rare.